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3.A.1.208.26
Mrp2 of 2133 aas.  Confers resistance to quinolone drugs including chloroquine, mefloquine and quinine (Mok et al. 2013).

Accession Number:A7XLD6
Protein Name:Multidrug resistance-associated protein 2
Length:2133
Molecular Weight:251339.00
Species:Plasmodium falciparum [5833]
Number of TMSs:10
Substrate Quinolones, chloroquine, Mefloquine, Quinine

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMRRRSVYNF DQGKHGYLMN HISWLNFVSF NWITQLLRCL KNDDFVLPCI EETSSIEHYS 
61:	TNLNRNVRNI QLRKYNKYNK YKNYCCSKYN DGNKSCSCST KNHTNKFHKR KKEDHFLKSS 
121:	GITYAVLKTF KYYLSLISFF HIIHTIFLIF VAVCIEKYVL LIKGGSNVVT LPFGFKNSKV 
181:	LFGFIVISVI FISQFFDALL CYYDFRLRVN MEVTVMYFLY KITLGNFNNQ LINRNDIYDD 
241:	HSEEGKGQHK NQCQYDENDQ NDENDQNDQN EQSDLRDIRH MHDKHVKHND EESKDSTNST 
301:	TYIKNNNNQM SHINDLSITN NMSDVHILSS IKNQDQNNSN NVSSMDSNTN YMSKTTCLTC 
361:	TGSEFNKEEK DEKKELLEEA KKKDKEVFDI SIYNIMFIDT PFLIYFITAL IELANMIIKF 
421:	IMSFYMFYYK MGSAAVLNGA LLIIIMYGLM FAFEFSSSLF KLKYLKYRDT RISNMHHILK 
481:	EFKLMKIFNW ESIAFDYVNM FRIKEMKICK IRTYLSSLSN YVNNISVNIV EVAIFFFYIR 
541:	SELKSNKTVS FSSLITPLFV YKSLISGVSN FPNIINNLIE GAINIKRINK YINYYLFNND 
601:	MNDYFKNSLN GMKSNTCNFQ NGNTNNVNGY VDDYVDGYVD DYVDDYVNDY VDDYVNDYVD 
661:	DYVNDYVDDY VNDYVDDYVD DYMDHMMEYN ININSKNGCS SKSRKNNKSF SKDHFSNHEQ 
721:	GTMQSFYKFL DTHKNKTKQK SDCIKKCSNN QLSKSNNNNV VGESNNSLFQ DRKGWYPKNK 
781:	HFKDNIVINM KNCYFSSKNN DDYILKNINL TLKNNSVVII LGNVGSGKTI FFYSLLGQFK 
841:	LSCGSFYLKN YIYKYMPILY VPQFNWISLG TIRSMILFGN KYDESIYYDV IVKSELFHDI 
901:	ISFKKKDMRY ISDEHSLSKG QKARICLARA LYHHYIHMKH MNLYYQKNEL INEKMKKISL 
961:	KRDDNHTAQR SNDNTPNNNN TDNNNTSDNN NTSNNNNTSD NNNTSDNNNT SDNNNTSNNN 
1021:	NTDNNNTSNN KNSCSKNLTE ERNISYLYLF DDLFTSLDPC ISKDIFYNLF CDKEKIQHFK 
1081:	KNSSFILSIS EIILNSFISS NCILNNMQYD VLIYKLENST LHYEGNLVDY IKKNNIVVKE 
1141:	DIVQTNKQCE KKSLTNEQVK SMLSLNEDWN YMHRVKKKSI TQKETTKNYD NNNDNNNDNN 
1201:	NDNNNDNNND NNNNNNNDNN NNNNNNVNVS KEILSCEIKT QDHYNNIHCS KTNFEKHNNS 
1261:	IYSKKENETR KIHSGDIKYH KFMVLKQFKT IYSFKTIYSF NTEETNDDEY NKTYYRKYTK 
1321:	VIQNYDNHCL EGKKKSFRNY KSINSYNEIL IKENMKVWED DTYYGNDYID EYEKIKKNVL 
1381:	SKLKYNYYIS CDYNNSDHFD FNEELKFKGN IKLETFWWYL KKIGRPLIIV IIIFMLLSIF 
1441:	TDEIKNLILF LASTILKSGD KKDEEILNQQ LVYLNYFILL PSISLLTTLI SFMLIAHGIV 
1501:	KSAIKVHTEV LLSILYAPIH AFYSNNLGNI INKFITDVNI LDNGIIKRIY KTFYTIFRFL 
1561:	FTLFLLIYMV KYTIVIFPFI MLIIYFFVFN KYSKGCKEAQ RGFLASHAPL CTIYSNTIIG 
1621:	KDVINLYKKN NYFLTLYKQK IFDFRNYTIF KWSITIWASL YVQLIVLALT FFYIIYPHFF 
1681:	FKHAKQDHEI NYEKEASTIG YCITFSCSLG FVIKSLLYDY THVEKEMCST QRLEECSKMI 
1741:	KDEGYSDDNI TLQNNDPTHE DNNNNNNNNN NEQDANLFKS VPGSYDPNDK ENMRKYKTEI 
1801:	VNNTKDMYSI INKDDMLTHS INNKNNKLKK LYTSPHIDIN KIKYGICFER VFVSYKKKIC 
1861:	VDRKNNKYEY VNEKSCLKNI NIYALKNQKI GIVGKSGAGK STMILSILGL IGTTRGRITI 
1921:	EGQDIKTLTL DERKNMIGVL PQSSFVFFHW NIRTFIDPYK DFTDDEIVDA FKLIGINLSY 
1981:	DDLDKYIYKQ QRQQQKKKNK NTHNLWKKKS FIDLTNSISL SDECIRYLSL VRLFLNRHKY 
2041:	KLILIDEIPV LNFCYNTKKL TNFFTTDIKS FDYIIRTFFQ NTTVLIIAHD ASTLSCCDFI 
2101:	YVIAKGEVVY KCSYKDVKTQ TELANLLQEK QLN