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3.A.1.5.7
The α-galactoside (melibiose, raffinose) uptake porter, AgpABCDF

Accession Number:Q9X4Y1
Protein Name:AgpA aka RB1567 aka SMB21647
Length:693
Molecular Weight:77407.00
Species:Rhizobium meliloti (Sinorhizobium meliloti) [382]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Periplasm1
Substrate Melibiose, Raffinose

Cross database links:

HEGENOM: HBG300093
RefSeq: NP_438106.1   
Entrez Gene ID: 1237898   
Pfam: PF00496   
BioCyc: SMEL266834:SMB21647-MONOMER   
KEGG: sme:SM_b21647   

Gene Ontology

GO:0042597 C:periplasmic space
GO:0005215 F:transporter activity
GO:0008643 P:carbohydrate transport

References (2)

[1] “Alpha-galactoside uptake in Rhizobium meliloti: isolation and characterization of agpA, a gene encoding a periplasmic binding protein required for melibiose and raffinose utilization.”  Gage D.J.et.al.   9791127
[2] “The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti.”  Finan T.M.et.al.   11481431

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MKTHRLNMTA SLLIGISAFA VQAFASEPTV VPEQPPFPAQ GKITYVSRDS ILEFKALREY 
61:	REPEWVTEKF VKAGKLPPVA ERLPKEPMVF KAGNMPDGMG VYGDVMRHVI GGRPEGWNYS 
121:	AGQTQGWGGI DIGMFECLTR TAPLFQVEAD DMEPLPNLAK SWDWSEDGRK LTMHLIEGAK 
181:	WSDGDPFDAD DVMFYWEDNV LDSSVSPLNG ATPETFGEGT TLKKIDQYTV EWTFKEAFPR 
241:	QHLFAMAYGT FCPGPSHILK TKHPKYAGTT YNEYKNGFPA EYMNLPVMGA WVPVAYRPDD 
301:	IIVLRRNPYY WKVDEAGNQL PYLNELHYKL STWADRDVQA IAGSGDISNL EQPENFVESL 
361:	KRAANESAPA RLAFGPRVIG YNMHMNFSGN GWGDPDERAK AVRELNRNLD FRKAVTMAVD 
421:	RKKLGEALVK GPFTAIYPGG LSSGTSFYDR NSTIYYPHDL EGAKVLLEKV GLKDTDGNGF 
481:	VNFPAGKLGG RDVEIVLLVN SDYSTDRNLA EGMVGQMEKL GLRVVLNALD GKQRDAANYA 
541:	GRFDWMIHRN TAEFASVVQN TPQLAPTGPR TSWHHRAPEG GEVDVMPHEQ ELVDIVNKFI 
601:	ASNDNDERTE LMKQYQKVAT TNVDTVGLTE YPGALIINKR FSNIPPGAPI FMFNWAEDTI 
661:	IRERVFVAAD KQGDYELYPE QLPGKPGESG PIN