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3.A.10.1.12
The K+-stimulated H+, Na+-PPase. Transports both Na+ and H+ noncompetitively in a single catalytic cycle (Luoto et al., 2013a, b).

Accession Number:B5JQT8
Protein Name:Putative K(+)-stimulated pyrophosphate-energized sodium pump
Length:715
Molecular Weight:74125.00
Species:Verrucomicrobiae bacterium DG1235 [382464]
Number of TMSs:16
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate H+, Na+

Cross database links:

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTPKLFWIAP GSALIGLLFA FLFFRQMTKQ NEGSARMREI AGYVSEGARA YLKQQYKVVT 
61:	FAFIVLAILF AILAYALHAQ NPWTPVIFVS GGLLSGLSGY FGMKTATASA SRTAQAASES 
121:	LDRGLRVAFR SGAVMGLCVV GLGLLAISIW FVVLTQIHYK EGAPNMPFIT TALLSFGMGA 
181:	SLQALFARVG GGIYTKAADV GADLVGKVEA GIPEDDPRNP ATIADNVGDF VGDVAGMGAD 
241:	LYESYCGSIL ATAALGAAAF AYDPELQLQA AVAPMVVAGL GILLSIIGIY LVHAKEGSSQ 
301:	HALLSALDRG VNFSALGIAA SSAVAIHLFD LPNPWGIWGA IVMGLIAGIA IGKATEYYTS 
361:	SDFKPTQTIV ANAETGPATV IISGLGTGMI STYVAVLAVS VSIMLSYTFA SGFQLSNMAH 
421:	GLYGIGFAAV GMLSTLGVTL ATDAYGPIAD NAGGNAEMSG LPPEVRQRTD ALDSLGNTTA 
481:	AIGKGFAIGS AALTAMALLA SYVFANPNIE SYKNANEMLA NYIQTHELHL LNPRVLIGLF 
541:	VGGLMAFLFC GLTMNAVGRT AKDMVEEVRR QFKADPGILK GDTVPDYASC VEISTLGAQR 
601:	EMIVPALIAV IAPVAIGLLF GPAGVVGLLT GGLTTGFVLA VFMANSGGAW DNAKKYIEEG 
661:	NMGGKGSDAH KAAVIGDTVG DPFKDTSGPS LNILIKLMTM VAIVTAGITL TYSIF