TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.10.1.17
H+-transporting pyrophosphatase of 816 aas (Drozdowicz et al. 2003). It is inhibited by 5-10 μM aminomethylenediphosphonate (AMDP) which also inhibits trypomastigotes and parasite growth (Drozdowicz et al. 2003).

Accession Number:B6KH90
Protein Name:H-translocating inorganic pyrophosphatase TV P,putative
Length:816
Molecular Weight:85296.00
Species:Toxoplasma gondii (strain ATCC 50861 / VEG) [432359]
Number of TMSs:17
Substrate H+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MGGRRRSFFL STAGALAPAV ATTTVSLIVL SSSFPLLSSS SPESEGDRFQ VTAATRDVPE 
61:	EASVAASREL SEEDATLRID KATTCLLLLP SIIGLFWAVY EAWKVSKIQM DGPLGDDNKR 
121:	LTDPLYLEMS GNIQQQLNMM KSISRCIADG AITFLTQEFK YMAVYIVVFS SILGIFVGIP 
181:	TMAAFVLGAL TSILCGFVGM KIAVYSNVRT CHEAWMELGR GFQVALTAGS VMGFALVSLG 
241:	CLTLVAIILL YRLPSLFGTN PEDQRALFEA VAGYGLGGSS IALFARVGGG IYTKAADVGA 
301:	DLSGKNEYGM SEDDPRNPAC IADNVGDNVG DVAGMGADLF GSLAEASCAG LVIAGASIAT 
361:	SASGGPQGLA HSWSGLMFPV LISSTGIFTG IFTVVLVRAC FSVRCYDDIE KALKWVMFIS 
421:	TGLEMPVLIL LSYFFLPSEF LLDGCQGTTA WWHAAVCVVL GLWAGLAIGY VTEYYTSHSY 
481:	FPVREISQTQ IVSAATGIIY GLALGYSSTV VPIICLGVTI LVSHTLCGMY GIALAALGML 
541:	STLTMGLMID GYGPISDNAG GIAEMAGLGP EVRSRTDALD AAGNTTAAVG KGYAIGSAAL 
601:	VSLALFGAFT VRAHITAVDV LDPWTFTGLL FGAMMPYAFS AMTMKSVGIA ASDMVQECLQ 
661:	QFPLIIQGNI EPQYKRCIEI STRASLHEMI APGALVICAP VAAGMMFGKN CTAGLLAGAL 
721:	VSGIQLAISA STSGSAWDNA KKYIESGALG ADHGKGSQAH KNAVTGDTVG DPLKDTSGPS 
781:	LNILIKLSAI ISLVFGAFIA EHFSNAQGGP AWVRVL