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3.A.10.3.3
Electrogenic H+-translocating Mg2+-pyrophosphatase, HhpA of 867 aas.  Inhibited by Na+ and regulated by K+ as well (Luoto et al. 2015).

Accession Number:F4H4X4
Protein Name:K(+)-insensitive pyrophosphate-energized proton pump
Length:867
Molecular Weight:91022.00
Species:Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547) [590998]
Number of TMSs:18
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate H+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSTSQSRSRV TSASPAAPPV DRPAARPRTP RSASRATAVG ALATLALLLS GCAATGEAGG 
61:	GSGHGGEAGL ALPDLGSVTI AGVPGRVWLG LGLVVCALGL AFGVTVVAQL KRLEVHDSMR 
121:	SVSELIYTTC KAYLVQQGRF LVVLWAFIAA VIVVYYRVLV GFDWGRVAVV IAFSLVGMAG 
181:	SYSVAWFGIR VNTYANSRTA FASLRGKALP LHRIPLRSGM AIGMVLISLE LAIMLVILLF 
241:	LPGDLAGACF IGFAVGESLG AAALRIAGGI FTKIADIGSD LMKIAFKIKE DDARNPGVIA 
301:	DCTGDNAGDS VGPSADGFET YGVTGVALVT FVLLGVPDPG VQAALLVWIF VVRTVMIAAS 
361:	GISYTVNDLV AQRRYAGAEG MDFEKPLTSL VWLTSAVCIV STYATTWLVL ADGTPGLWWK 
421:	LATIISCGTL AGALIPELVK VFTSTGSRHT REVVASSKEG GPSLNILSGL VAGNFSAYWL 
481:	GMTIVALMGG AYLVSELGLD EVMHAPAVFA FGLVAFGFLG MGPVTIAVDS YGPVTDNAQS 
541:	VYELSGVEDV DGIDEDLRAS HGFVPAWERA KQMLEENDGA GNTFKATAKP VLIGTAVVGA 
601:	TTMIFSIIMG LTDGLTTGLE NLSLLHPPFL LGLVAGGSVI YWFTGASIQA VTTGAYRAVE 
661:	FIRTHIRLDG SEKASEEDSR RVVEICTQYA QRGMLTMFLG VFFATLAFAF VEPYFFVGYL 
721:	ISIALFGLYQ AIFMANAGGA WDNAKKIVET ELHANGTPLH DATVVGDTVG DPFKDTSSVA 
781:	LNPVIKFTTL FGLLAVDLAV QLSGQGRHAL VLTLAAVFFL ASTYFVHRSF YGMRIQASTE 
841:	TPTPDDEPAE LLPQPGTPAD DAVPTRV