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3.A.10.3.5
H+-translocating pyrophosphatase of 836 aas, HppA (Luoto et al. 2015)

Accession Number:C7RKM6
Protein Name:K(+)-insensitive pyrophosphate-energized proton pump
Length:836
Molecular Weight:89317.00
Species:Accumulibacter phosphatis (strain UW-1) [522306]
Number of TMSs:18
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate H+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTFSYSALAP PWRSLARHLL LAFIFAIGTA TLPALAATEH VSEANLVLPD LGDVSLVTFL 
61:	GGISGWTLLS WGLLVSLGGL VFGAVIYSQI QRLPVHRSMA EVSELIYETC KTYMLTQGKF 
121:	LLILEAFTAV IMIGYFYVVQ ELPVPDVAMI LAFSLVGIAG SFGVAWFGIR INTLANSRTA 
181:	FASLAAKPYP VYAIPIKSGI SIGMLLISTE LLIMLCIMLF VPAALAGKCF IGFAIGESLG 
241:	AAALRIAGGI FTKIADIGSD LMKIEFGIQE DDARNPGVIA DCAGDNAGDS VGPTADGFET 
301:	YGVTGVALIS FIMLAVPEAA VQVQLLVWLF VMRVMMIVAS GISYLGNQMV ARRRYGNKQR 
361:	FNFEAPLTSL VWITSVVSVV ITFIVSYLLM GSFALDGKPY SNLWWQLSLI ITLGTLAGAI 
421:	IPEVVKVFTS TNSRHVREVV TASEAGGASL NILSGIVAGY FSAFWIGVII VGLMSGAYVV 
481:	SQFDLTAVIN PDDAKAAMMA AVFSFGLVAF GFLGMGPVTI AVDSYGPVTD NAQSVYELSM 
541:	IEQVPGIQAE VKRDFGFDLD FRSAKFLLEE NDGAGNTFKA TAKPVLIGTA VVGATTMVFS 
601:	IVMLLTAGLT DNLDKLSLLH PPFLLGLIAG GATIFWFSGA STQAVSTGAY RAVEFISTHI 
661:	RLDEVVKASQ KDSKKVVEIC TIYAQKGMFN IFMAVFFGTL ACAFIEPFFF IGYLISLAII 
721:	GLYQAVFMAN AGGAWDNAKK IVETEMHAKG TDLHNASVVG DTVGDPFKDT ASVAMNPIIK 
781:	FTTLFGLLAV EMAVGLEVQG QQVLVYALAA LFLAVNLVFV FRSFYGMRIL AKKENG