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3.A.12.2.1
The major protein required for plasmid transfer, Tra

Accession Number:P22409
Protein Name:Tra aka KilA
Length:621
Molecular Weight:66420.00
Species:Streptomyces lividans [1916]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate DNA

Cross database links:

Pfam: PF01580   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0003677 F:DNA binding
GO:0007049 P:cell cycle
GO:0051301 P:cell division
GO:0007059 P:chromosome segregation

References (1)

[1] “Complete nucleotide sequence of the Streptomyces lividans plasmid pIJ101 and correlation of the sequence with genetic properties.”  Kendall K.J.et.al.   3170481

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MAPTLAPFAA RWDAEADRRM ALRTPEHLKA LMDAQKGYNS ARSTAATAKS QRTAARAASK 
61:	NPLSTVRRAA RTADKAARTH RDQAKTKLKA ARKDYPATLR ARAVQAHAMH AVPGAGISAL 
121:	GWDQAGAWPV AGSLALIAAN VAALVIGRRK VAVAVADELS AEERRLVERL DPSYWAQHAD 
181:	ERGLVGTVTT PVQVTPAGLV TTVRLDGRWK PSAFKAKHEE IRALLGARTD LRMEIKAGSH 
241:	GDRAVITLRT RSAADGIDLT GWTPGAPWGV DTVTGEPVQV PLGRRMLIAG TSGSGKSWST 
301:	RALLAEGSEY ADHRLVVVDP KRVEAINWQH RARTAISIED VLDVTDELVE EMHERLELIP 
361:	RGQDVIQISP ERPRITVFID EGAEVIAMAK KTRAKGSKEE PGDPDWSRIM ENLSTLARMA 
421:	RAAEIILIWA TQKPTMDAKG GIDPQISAQI TYRAALALST SGESRVVFGE DATEKGWHAH 
481:	ELPMPGVAML RSGPKVQPHP INTRAFSPAD VIALPDRPVW RRQESPARSA GASAPAPLRL 
541:	VKETAPAAEV PAQPTKAPTN REKVAAAIGT GATTVADVAT VTGINKGSVS KAVKQLLDAG 
601:	EVLRSEDGSL SVVTQVGEVS A