TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*3.A.15.1.1









The pullulanase secretion system
Bacteria
Proteobacteria
PulC-O and PulS of Klebsiella pneumoniae
*3.A.15.2.1









The pilin secretion/fimbrial assembly system. The PilB and PilT ATPases act antagonistically in Type IV pilus function in Myxococcus xanthus. ATP binding and hydrolysis by PilT are essential for T4P extension while ATP binding and hydrolysis by PilB are essential for T4P retraction. Thus, PilB and PilT act at distinct steps in the T4P extension/retraction cycle (Jakovljevic et al., 2008).
Bacteria
Proteobacteria
PilABCDEQTU-FimTU of Pseudomonas aeruginosa
*3.A.15.2.2









α-helical pore-forming toxin-coregulated pilus biosynthesis protein E, TcpE, of 340aas and 3TMSs with an internal repeat (Kolappan and Craig 2013).

Bacteria
Proteobacteria
TcpE of Vibrio cholerae (P0C6C9)
*3.A.15.3.1









The Legionella secretion pathway (Lsp)/fimbrial assembly system, LspC-M (required for survival and replication in the host cell; Hales and Shuman, 1999; Rossier et al., 2004; De Buck et al., 2007)

Bacteria
Proteobacteria
The LspC-M system of Legionella pneumophila:
Prepilin peptidase, PilD (287aas; O68433)
Type IV pseudopilin, LspF (126aas; Q9XD72)
Type IV pseudopilin, LspG (140aas; Q9XD71)
Type IV pseudopilin, LspH (161aas; Q9XD70)
Type IV pseudopilin, LspI (125aas; Q9XD69)
Type IV pseudopilin, LspJ (205aas; Q9XD68)
Type IV pseudopilin, LspK (322aas; Q9XD67)
Outer membrane secretin, LspD (730aas; Q9AGM8)
ATPase, LspE (494aas;Q9AGM7)
Conserved IISP protein, LspC (169aas; Q5ZX38)
Conserved IISP protein, LspL (379aas; Q5ZUD0)
Conserved IISP protein, LspM (156aas; Q5ZUC9)
*3.A.15.4.1









The Leptospiral type II protein secretion system (Gsp)/fimbrial assembly system, PilD/GspCDEFGHIJKLM (Buyuktimkin and Saier 2015).

Bacteria
Spirochaetes
PilD/GspCDEFGHIJKLM of Leptospira interrogans