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3.A.3.5.28
The putative copper ATPase, Ape2

Accession Number:Q9YBZ6
Protein Name:Cation-transporting ATPase
Length:838
Molecular Weight:90210.00
Species:Aeropyrum pernix [56636]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Cu+

Cross database links:

HEGENOM: HBG507745
RefSeq: NP_147955.2   
Entrez Gene ID: 1446027   
Pfam: PF00122    PF00403    PF00702   
BioCyc: APER272557:APE1454-MONOMER   
KEGG: ape:APE_1454.1   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0004008 F:copper-exporting ATPase activity
GO:0046872 F:metal ion binding
GO:0006754 P:ATP biosynthetic process
GO:0030001 P:metal ion transport

References (1)

[1] “Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1.”  Kawarabayasi Y.et.al.   10382966

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSGVTLVKEK LSIKGMHCAT CGLTVEKALR SLPGVVEASA DPVTGEAVIA YEPGSVRLSD 
61:	VVKAIRSVGY DVVLAEAVIR VPSMSSIDDE RVVEETLLKM KGVAEVYASH TNKTVVVRYN 
121:	PHATKPEEVL EALRKAGYKA EMAEGKSLVE AEAEEERRLL LDGLISITAS IVYYILLALE 
181:	RLAGVEAAGA VLPYYGAVVF AIVLLGPGRR FLVGAYRSLK NGTPGMDALV SLGTLSIYFY 
241:	SLAATLNIIR GELYYEGIGL IIGFVLIGRY IESKVKKGTG KAVENLAKLK PQKARVLRGR 
301:	REVEVDVSEV KPGDLVVVRQ GERIPVDGYV VQGKAYVDES VFTGEPIPVE KKPGDLVLAG 
361:	SMVSSGWLHI SATRTSGDTA IDRIARLIAY SQAGKMDIQR LADRVSGMFF WAVLCIASLT 
421:	FTAWLFLGGL ETAIIRAASV FLISCPCALG LATPTASSAG VGVAARAGIL VRNVVAFERL 
481:	AKASIVVFDK TGTLTLGMPR VAAVEAVDGY SEKEILELAA SAEKWSEHPL ARAIIDAYME 
541:	VAGRGPEDPD NAEVFPGMGV YAEVGGRSVV VGNRKIMDGF EVDIKTLEKI AEEWQSRGAT 
601:	TVFVAIDGKP AGVIAIRDEP RPEARETVDW LEKLGLKVMM LTGDSEGTAR AIARELDIEE 
661:	YRAGVSPEGK AEVIRELQKK GHVVVMVGDG VNDAPSLARA DVGIAVANAT DVSVEAGDIV 
721:	LIKGDLRRVP LAVVISRKTY NTIKFNLFWA FIYNVTLIPV AAGAFAWAGI TLRPELAAAA 
781:	MALSSITVTS ISYRLSKWKP RLPGDYETYD NKEEKEESKE EFERITREEK ALAAGRQQ