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3.A.3.9.2
K+-ATPase (efflux)

Accession Number:P22189
Protein Name:ATC3 aka Cta3 aka SPBC839.06 aka SPBC24E9.06
Length:1037
Molecular Weight:115327.00
Species:Schizosaccharomyces pombe (Fission yeast) [4896]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate K+

Cross database links:

eggNOG: fuNOG05186
HEGENOM: HBG456486
RefSeq: NP_595246.1   
Entrez Gene ID: 2541204   
Pfam: PF00689    PF00690    PF00122    PF00702   
KEGG: spo:SPBC839.06   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005524 F:ATP binding
GO:0005388 F:calcium-transporting ATPase activity
GO:0006754 P:ATP biosynthetic process
GO:0070588 P:calcium ion transmembrane transport
GO:0006874 P:cellular calcium ion homeostasis

References (3)

[1] “Calcium homeostasis and transport are affected by disruption of cta3, a novel gene encoding Ca2(+)-ATPase in Schizosaccharomyces pombe.”  Ghislain M.et.al.   2145281
[2] “The genome sequence of Schizosaccharomyces pombe.”  Wood V.et.al.   11859360
[3] “Phosphoproteome analysis of fission yeast.”  Wilson-Grady J.T.et.al.   18257517

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVTINISNPV YFSDIKDVES EFLTSIPNGL THEEAQNRLS EYGENRLEAD SGVSAWKVLL 
61:	RQVLNAMCVV LILAAALSFG TTDWIEGGVI SAIIVLNITV GFIQEYKAEK TMDSLRTLAS 
121:	PMAHVTRSSK TDAIDSHLLV PGDVVVLKTG DVVPADLRLV ETVNFETDEA LLTGESLPVI 
181:	KDAHATFQMN EDVPIGDRIN LAYSSSIVTK GRAKGICYAT GMQTQIGAIA AGLRQKGKLF 
241:	QRPEKDEPNY RRKLNKYYLK VTSYYVQRVL GLNVGTPLQR KLTVLAYILF CIAIILAIIV 
301:	MAAHSFHVTN EVSIYAISLG ISIIPESLIA VLSITMAMGQ KNMSKRRVIV RKLEALEALG 
361:	GVTDICSDKT GTITQGKMIT RRVWIPSYGY LSVDTSDANN PTIGTVSGLE AAMQDVLKEK 
421:	KQEMKNIDPS NQPSDQFIPL LKTCALCNLS TVNQTETGEW VVKGEPTEIA LHVFSKRFNY 
481:	GKEDLLKTNT FVREYPFDSE IKRMAVIYED QQGQYTVYAK GAVERILERC STSNGSTLEE 
541:	PDRELIIAQM ETLAAEGLRV LALATKVIDK ADNWETLPRD VAESSLEFVS LVGIYDPPRT 
601:	ESKGAVELCH RAGIRVHMLT GDHPETAKAI AREVGIIPPF ISDRDPNMSW MVMTGSQFDA 
661:	LSDEEVDSLK ALCLVIARCA PQTKVKMIEA LHRRKAFVAM TGDGVNDSPS LKQANVGIAM 
721:	GQNGSDVAKD ASDIVLTDDN FSSIVNAIEE GRRMFDNIMR FVLHLLVSNV GEVILLVVGL 
781:	AFRDEVHLSV FPMSPVEILW CNMITSSFPS MGLGMELAQP DVMERLPHDN KVGIFQKSLI 
841:	VDMMVYGFFL GVVSLMTWVV IMYGFGTGNL SYDCNAHYHA GCNDVFKARS AVFAVVTFCI 
901:	LIMAVEVKNF DNSLFNLHGI PWGEWNFRYF LHTLVENKFL AWAIALAAVS VFPTIYIPVI 
961:	NRDVFKHTYI GWEWGVVAVA VMFYFFYVEI WKSIRRSLTN PQKKGKFRRT LSNTITTESK 
1021:	LSEKDLEHRL FLQSRRA