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3.E.1.4.1
Heat shock protein HSP30

Accession Number:P25619
Protein Name:HS30 aka HSP30 aka YCR021C aka YCR21C
Length:332
Molecular Weight:37045.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P25619
eggNOG: fuNOG10073
HEGENOM: HBG395442
DIP: DIP-4586N
RefSeq: NP_009950.1   
Entrez Gene ID: 850385   
Pfam: PF01036   
KEGG: sce:YCR021C   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0001950 C:plasma membrane enriched fraction
GO:0042802 F:identical protein binding
GO:0005216 F:ion channel activity
GO:0006811 P:ion transport
GO:0032780 P:negative regulation of ATPase activity
GO:0006950 P:response to stress

References (8)

[1] “Isolation and sequence of HSP30, a yeast heat-shock gene coding for a hydrophobic membrane protein.”  Regnacq M.et.al.   8319300
[2] “The complete DNA sequence of yeast chromosome III.”  Oliver S.G.et.al.   1574125
[3] “Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae.”  Ficarro S.B.et.al.   11875433
[4] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[5] “A proteomics approach to understanding protein ubiquitination.”  Peng J.et.al.   12872131
[6] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[7] “Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.”  Smolka M.B.et.al.   17563356
[8] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNDTLSSFLN RNEALGLNPP HGLDMHITKR GSDWLWAVFA VFGFILLCYV VMFFIAENKG 
61:	SRLTRYALAP AFLITFFEFF AFFTYASDLG WTGVQAEFNH VKVSKSITGE VPGIRQIFYS 
121:	KYIAWFLSWP CLLFLIELAA STTGENDDIS ALDMVHSLLI QIVGTLFWVV SLLVGSLIKS 
181:	TYKWGYYTIG AVAMLVTQGV ICQRQFFNLK TRGFNALMLC TCMVIVWLYF ICWGLSDGGN 
241:	RIQPDGEAIF YGVLDLCVFA IYPCYLLIAV SRDGKLPRLS LTGGFSHHHA TDDVEDAAPE 
301:	TKEAVPESPR ASGETAIHEP EPEAEQAVED TA