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3.E.1.7.1
Channelrhodopsin-1 (chlamyrhodopsin-3) (ChR1; Cop3; CSOA) (light-gated proton channel) (Nagel et al., 2003). TMSs 1 and 2 are the main structures involved in desensitization involving the stabilization of the protein's conformation and the alteration of the charge distribution around the retinal-Schiff base (Zamani et al. 2017).

Accession Number:Q93WP2
Protein Name:ACOP1
Length:712
Molecular Weight:76442.00
Species:Chlamydomonas reinhardtii [3055]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate protons

Cross database links:

Pfam: PF01036   

Gene Ontology

GO:0016020 C:membrane
GO:0005216 F:ion channel activity
GO:0006811 P:ion transport

References (1)

[1] “Channelrhodopsin-1: a light-gated proton channel in green algae.”  Nagel G.et.al.   12089443
Structure:
3UG9     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSRRPWLLAL ALAVALAAGS AGASTGSDAT VPVATQDGPD YVFHRAHERM LFQTSYTLEN 
61:	NGSVICIPNN GQCFCLAWLK SNGTNAEKLA ANILQWITFA LSALCLMFYG YQTWKSTCGW 
121:	EEIYVATIEM IKFIIEYFHE FDEPAVIYSS NGNKTVWLRY AEWLLTCPVI LIHLSNLTGL 
181:	ANDYNKRTMG LLVSDIGTIV WGTTAALSKG YVRVIFFLMG LCYGIYTFFN AAKVYIEAYH 
241:	TVPKGICRDL VRYLAWLYFC SWAMFPVLFL LGPEGFGHIN QFNSAIAHAI LDLASKNAWS 
301:	MMGHFLRVKI HEHILLYGDI RKKQKVNVAG QEMEVETMVH EEDDETQKVP TAKYANRDSF 
361:	IIMRDRLKEK GFETRASLDG DPNGDAEANA AAGGKPGMEM GKMTGMGMGM GAGMGMATID 
421:	SGRVILAVPD ISMVDFFREQ FARLPVPYEL VPALGAENTL QLVQQAQSLG GCDFVLMHPE 
481:	FLRDRSPTGL LPRLKMGGQR AAAFGWAAIG PMRDLIEGSG VDGWLEGPSF GAGINQQALV 
541:	ALINRMQQAK KMGMMGGMGM GMGGGMGMGM GMGMGMAPSM NAGMTGGMGG ASMGGAVMGM 
601:	GMGMQPMQQA MPAMSPMMTQ QPSMMSQPSA MSAGGAMQAM GGVMPSPAPG GRVGTNPLFG 
661:	SAPSPLSSQP GISPGMATPP AATAAPAAGG SEAEMLQQLM SEINRLKNEL GE