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4.A.1.1.14
Glucose porter GlcB (IICBA). Glucose uptake is inhibited by methyl-α-D-glucoside, methyl-β-D-glucoside, p-nitrophenyl-α-D-glucoside, o-nitrophenyl-β-D-glucoside and salicin, but not by 2-deoxyglucose. Mannose and N-acetylglucosamine are not transported (Christiansen and Hengstenberg, 1999).

Accession Number:Q53922
Protein Name:PTS system glucoside-specific EIICBA component
Length:692
Molecular Weight:75403.00
Species:Staphylococcus carnosus (strain TM300) [396513]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate glucose

Cross database links:

Entrez Gene ID: 7551629   
Pfam: PF00358    PF00367    PF02378   
KEGG: sca:Sca_1000   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005355 F:glucose transmembrane transporter activity
GO:0016301 F:kinase activity
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (4)

[1] “Cloning and sequencing of two genes from Staphylococcus carnosus coding for glucose-specific PTS and their expression in Escherichia coli K-12.”  Christiansen I.et.al.   8602153
[2] “Genome analysis of the meat starter culture bacterium Staphylococcus carnosus TM300.”  Rosenstein R.et.al.   19060169
[3] “Staphylococcal phosphoenolpyruvate-dependent phosphotransferase system -- two highly similar glucose permeases in Staphylococcus carnosus with different glucoside specificity: protein engineering in vivo?”  Christiansen I.et.al.   10537210
[4] “Regulation of the glucose-specific phosphotransferase system (PTS) of Staphylococcus carnosus by the antiterminator protein GlcT.”  Knezevic I.et.al.   10974121

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKNLLKKFFG QLQRIGKALM LPVAILPAAG ILLTFGNAMH NEQILHFAPW MQHHYIQLIS 
61:	QIMEASGQVI FDNLPLLFAM GTALGLAGGD GVAGIAALVG YLIMSATMGK IAGITIDDIF 
121:	SYADGAKTLG QSAKDPAHAL VLGIPTLQTG VFGGIIIGAL AAWCYNKFYN IQLPQFLGFF 
181:	AGKRFVPIIT SLVAIVTGIV LSFVWPPVQD GLNNLSNFLL GKNLALTTFI FGIIERSLIP 
241:	FGLHHIFYAP FWFEFGHYVN ESGNLVRGDQ RIWMAQYQDG VPFTAGAFTT GKYPFMMFGL 
301:	PAAAFAIYRQ AKPERRKVVG GLMLSAALTS FLTGITEPLE FSFLFVAPIL YVAHVILAGT 
361:	SFLIMHLLHV QIGMTFSGGF IDYILYGLLS WDRSNALLVI PVGIAYALIY YFLFTFLIKK 
421:	LNLKTPGRED KEVESKDVSV SELPFEVLEA MGNKDNIKHL DACITRLRVE VRDKGLVDVE 
481:	KLKQLGASGV LEVGNNMQAI FGPKSDQIKH DMQQIMDGKI TSPAETTVTE DGDVETAEIV 
541:	AEGGAVIYAP ITGEAVDLSE VPDKVFSAKM MGDGIAIKPE TGEVVAPFDG KVKMIFPTKH 
601:	AIGLESKDGI ELLIHFGLET VKLDGEGFEI LVKENDNIVL GQPLMKVDLN YIKEHADDTI 
661:	TPIIITNAGS ANIEVLHTGK VEQGEKLLLV NN