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4.A.1.1.4
The α-glucoside-specific IICB (MalB) (substrates probably include glucosyl-α-fructose disaccharides: trehalurose (α-1,1), turanose (α-1,3), malturose (α-1,4), leucrose (α-1,5) and palatinose (α-1,6)).

Accession Number:O06900
Protein Name:MalB aka PTAB
Length:526
Molecular Weight:57313.00
Species:Fusobacterium mortiferum [850]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Trehalurose, Turanose, Malturose, Leucrose, Palatinose

Cross database links:

Pfam: PF00367    PF02378   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0016301 F:kinase activity
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (2)

[1] “Metabolism of sucrose and its five isomers by Fusobacterium mortiferum.”  Pikis A.et.al.   11882720
[2] “6-phospho-alpha-D-glucosidase from Fusobacterium mortiferum: cloning, expression, and assignment to family 4 of the glycosylhydrolases.”  Bouma C.L.et.al.   9209025

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLKHFQRLGG ALFAPVLLFP FAGLVVALTI ILKNPDFVGE LANTNGTFYK MITVIEEGGW 
61:	TVFRQLPLIF AIGLPIGLAK KAHPRACLAV LATYLTYNYF ISAILTFWGP SFGVDFTQNV 
121:	GGVSGLTTIA GIKTLDTSIV GAIVISGITI YIHNKFFDTK LPDFLGTFQG TTLVSAIAFV 
181:	VMIPCAYITC LVWPKIQMGI SSLQALMVTS GTFGVWLYTF LERILIPTGL HHFIYGPFIF 
241:	GPAVVDTGIQ VAWAENLLNF ANSTQPLKEL FPQGGFALHG NSKIFGCIGI ALAMYKTARP 
301:	EKKKIVSGLL IPAALTAALV GITEPLEFTF LFIAPFLFVV HAVLAATMAA VMYAFGVVKY 
361:	GSGIIEIAAL NWLPLMKNHS GVMFTQLAIG VVFIGIHYLV FKFLIEKYNV KTSGREDEEE 
421:	ETKLYTKADW KAKNGEGKET NSSDLYSGKA KAFLEAFGGK DNIEQVNNCA TRLRISVKDE 
481:	KKVGPDIQFK AAGAHGVVRN GKAFQVIVGL SVPQVRESFE NLMEQN