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4.A.1.1.7
The N-acetylglucosamine IICB porter (NagP; YflF) (45% identical to 4.A.1.1.2) (Plumbridge 2015).

Accession Number:O34521
Protein Name:Phosphotransferase system (PTS) N-acetylglucosamine-specific enzyme IICB component
Length:452
Molecular Weight:48580.00
Species:Bacillus subtilis [1423]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate N-acetylglucosamine

Cross database links:

HEGENOM: HBG571563
RefSeq: NP_388651.1   
Entrez Gene ID: 938807   
Pfam: PF00367    PF02378   
BioCyc: SUBTI:BSU07700-MONOMER   
KEGG: bsu:BSU07700   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0019866 C:organelle inner membrane
GO:0005886 C:plasma membrane
GO:0016301 F:kinase activity
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (2)

[1] “Cloning and sequencing of a 35.7 kb in the 70 degree-73 degree region of the Bacillus subtilis genome reveal genes for a new two-component system, three spore germination proteins, an iron uptake system and a general stress response protein.”  Yamamoto H.et.al.   9272861
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLSFLQKLGK SFMLPIAVLP AVGIILALGR EDVFNIPFVY QAGTAVFDHL PLIFAIGIAI 
61:	GISKDSNGAA GLSGAISYLM LDAATKTIDK TNNMAVFGGI IAGLIAGYTY NRFKDTKLPE 
121:	YLGFFSGRRL VPILTAIITI ILAGIFGVVW PPIQSCINSF GEWMLGLGGI GAGIFGLFNR 
181:	LLIPLGLHHV LNNIFWFQFG EYNGVTGDLA RFFAKDPTAG TYMTGFFPIM MFGLPAACLA 
241:	MVVTAKPSKR KATAGMMIGF ALTAFITGIT EPIEFAFMFL SPLLYAVHAV LTGLSLFIVN 
301:	WLGIRSGFSF SAGAIDYVLS YGIAEKPLLL LLVGICYAAV YFIVFYVLIK ALNLKTPGRE 
361:	DDDVDEVLDE NTVQDVNENI MLKGLGGKEN LQTIDHCATR LRLTVKDTAL VDEALLKKAG 
421:	AKGVVKSGGQ SVQVIIGPNV EFAAEELRAA VK