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4.A.1.1.8
The maltose IICB porter (MalP; GlvC) (56% identical to 4.A.1.1.4) (Yamamoto et al., 2001).

Accession Number:P54715
Protein Name:PTS system, arbutin-like IICB component aka Phosphotransferase enzyme II, CB component aka EC 2.7.1.69
Length:527
Molecular Weight:58055.00
Species:Bacillus subtilis [1423]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Maltose

Cross database links:

HEGENOM: HBG571563
RefSeq: NP_388701.1   
Entrez Gene ID: 939713   
Pfam: PF00367    PF02378   
KEGG: bsu:BSU08200   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0016301 F:kinase activity
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (3)

[1] “Determination of a 12 kb nucleotide sequence around the 76 degrees region of the Bacillus subtilis chromosome.”  Yamamoto H.et.al.   8704981
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “Regulation of the glv operon in Bacillus subtilis: YfiA (GlvR) is a positive regulator of the operon that is repressed through CcpA and cre.”  Yamamoto H.et.al.   11489864

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMQKIQRFGS AMFVPVLLFA FAGIIVGIST LFKNKTLMGP LADPDGFWYQ CWYIIEQGGW 
61:	TVFNQMPLLF AIGIPVALAK KAQARACLEA LTVYLTFNYF VSAILTVWGG AFGVDMNQEV 
121:	GGTSGLTMIA GIKTLDTNII GAIFISSIVV FLHNRYFDKK LPDFLGIFQG STYIVMISFF 
181:	IMIPIALAVS YIWPMVQSGI GSLQSFLVAS GAVGVWIYTF LERILIPTGL HHFIYTPFIY 
241:	GPAVAEGGIV TYWAQHLGEY SQSAKPLKEL FPQGGFALHG NSKIFGIPGI ALAFYVTAKK 
301:	EKKKLVAGLL IPVTLTAIVA GITEPIEFTF LFISPFLFAV HAVLAATMST VMYMAGVVGN 
361:	MGGGLIEAVT LNWIPLFGSH GMTYVYQILI GLSFTAIYFF VFRFLILKFN IATPGREKDE 
421:	QQETKLYSKK EYRERKNKDE TASAAETADD TAFLYIEALG GKDNITEVTN CATRLRVSVK 
481:	DETKVEPDSV FRALGAHGVV RNGKAFQVII GLSVPQMRER VEKILNQ