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4.A.1.2.1
Sucrose porter (ScrA)

Accession Number:P08470
Protein Name:Sucrose IIBC aka SCRA aka PTSB
Length:456
Molecular Weight:47865.00
Species:Salmonella typhimurium [90371]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Sucrose

Cross database links:

Pfam: PF00367    PF02378   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0016301 F:kinase activity
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (4)

[1] “DNA sequence of the gene scrA encoding the sucrose transport protein EnzymeII(Scr) of the phosphotransferase system from enteric bacteria: homology of the EnzymeII(Scr) and EnzymeII(Bgl) proteins.”  Ebner R.et.al.   3285123
[2] “Molecular analysis of two ScrR repressors and of a ScrR-FruR hybrid repressor for sucrose and D-fructose specific regulons from enteric bacteria.”  Jahreis K.et.al.   8412665
[3] “Molecular analysis of the scrA and scrB genes from Klebsiella pneumoniae and plasmid pUR400, which encode the sucrose transport protein Enzyme II Scr of the phosphotransferase system and a sucrose-6-phosphate invertase.”  Titgemeyer F.et.al.   8628219
[4] “Plasmid-mediated sucrose metabolism in Escherichia coli: characterization of scrY, the structural gene for a phosphoenolpyruvate-dependent sucrose phosphotransferase system outer membrane porin.”  Hardesty C.et.al.   1846143

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDFEQISCSL LPLLGGKENI ASAAHCATRL RLVLVDDSLA DQQAIGKVEG VKGCFRNAGQ 
61:	MQIIFGTGVV NKVYAAFTQA AGISESSKSE AADIAAKKLN PFQRIARLLS NIFVPIIPAI 
121:	VASGLLMGLL GMVKTYGWVD PGNAIYIMLD MCSSAAFIIL PILIGFTAAR EFGGNPYLGA 
181:	TLGGILTHPA LTNAWGVAAG FHTMNFFGFE IAMIGYQGTV FPVLLAVWFM SIVEKQLRRA 
241:	IPDALDLILT PFLTVIISGF IALLIIGPAG RALGDGISFV LSTLISHAGW LAGLLFGGLY 
301:	SVIVITGIHH SFHAVEAGLL GNPSIGVNFL LPIWAMANVA QGGACLAVWF KTKDAKIKAI 
361:	TLPSAFSAML GITEAAIFGI NLRFVKPFIA ALIGGAAGGA WVVSVHVYMT AVGLTAIPGM 
421:	AIVQASSLLN YIIGMVIAFG VAFTVSLVLK YKTDAE