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4.A.1.2.10
Sucrose porter and regulatory sensor, IIBC (SacX) (43% identical to 4.A.1.2.1) (Tortosa and Le Coq 1995). The IIA domains of PtsA, GamP, PtsG and GmuA can all phosphorylate the IIB domain in the SacX sensor (Morabbi Heravi and Altenbuchner 2018).

Accession Number:P15400
Protein Name:Sucrose porter IIBC aka Negative regulatory protein of sacY
Length:459
Molecular Weight:49024.00
Species:Bacillus subtilis [1423]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Sucrose

Cross database links:

HEGENOM: HBG673521
RefSeq: NP_391720.1   
Entrez Gene ID: 937333   
Pfam: PF00367    PF02378   
KEGG: bsu:BSU38410   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0016301 F:kinase activity
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (5)

[1] “Nucleotide sequence of the sacS locus of Bacillus subtilis reveals the presence of two regulatory genes.”  Zukowski M.M.et.al.   2116367
[2] “Bacillus subtilis genome project: cloning and sequencing of the 97 kb region from 325 degrees to 333 degrees.”  Glaser P.et.al.   7934828
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “A gene encoding a tyrosine tRNA synthetase is located near sacS in Bacillus subtilis.”  Glaser P.et.al.   1806041
[5] “Sites of positive and negative regulation in the Bacillus subtilis antiterminators LicT and SacY.”  Tortosa P.et.al.   11580842

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MHKEIAKELL LLAGGKNNII SISHCTTRLR FDVKDETKID IHAIENLQGV QGTFFRYGLF 
61:	QIIFGAGVVN KIYKEVVHVW ETAPSEEPVH QKKASRKLNP AAAFAKTLSD IFVPIIPAIT 
121:	ASGLLMGLIG MIKVFHWFAA GSPWIKMLDL VSSTAFILLP ILVGFSAARQ FGSNPYLGAV 
181:	IAGLLTHPDL LDPSMLGSKT PSSLDIWGLH IPMMGYQGSM IPILLSVFVM SKIEKLLKSI 
241:	VPKSLDVVII PFITVMVTGC LALIVMNPAA SIIGQIMTQS IVYIYDHAGI AAGALFGGIY 
301:	STIVLSGLHH SFYAIEATLL ANPHVGVNFL VPIWSMANVA QGGAGLAVFL KTKQSSLKKI 
361:	ALPASLTAFL GIVEPIVFGV NLKLIRPFIG AAIGGAIGGA YVVAVQVVAN SYGLTGIPMI 
421:	SIVLPFGAAN FVHYMIGFLI AAVSAFIATL FLGFKEETE