TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


4.A.1.2.5
β-glucoside (methyl-β-glucoside, salicin, arbutin) porter, BglF [a V317A or V317M mutation allows it to transport cellobiose as well] (Kotrba et al., 2003)

Accession Number:Q8GGK3
Protein Name:BglF
Length:618
Molecular Weight:64826.00
Species:Corynebacterium glutamicum (Brevibacterium flavum) [1718]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Methyl-beta-glucosides, salicin, arbutin

Cross database links:

Pfam: PF00358    PF00367    PF02378   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0016301 F:kinase activity
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (1)

[1] “A single V317A or V317M substitution in Enzyme II of a newly identified beta-glucoside phosphotransferase and utilization system of Corynebacterium glutamicum R extends its specificity towards cellobiose.”  Kotrba P.et.al.   12777497

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MATKTDFSPL VADVVTALGG ADNVRSVTHC ATRLRFKIKD SDKADIAKAG KISGVITAIN 
61:	SGGQHQVVIG NDVPLAYQAL MDVPGMRAKG IKDGDAEVDD DGGSEDKNWL NKFIDLISAL 
121:	FSPIVWALAG IGLGKAGLTL ATTVGILDAE SSTHTIFNAM FDGLFYFLPF FLAITAAKRF 
181:	KVNQFIALAI VAALLHPTME AMVGTEGVTF LGLPLTMMSY SSSVIPVVVS VWLAGYLQRW 
241:	LEKVLPGAVR NFFTPLIVVL VMVPLVLFTI GPVTIGAANA LSNGIGFLFE TVPWLAGGLM 
301:	GAFWQVFVMF GLHWGLVPVM INDIATQGFS YMMAPLMAAI FGQVGAALAV WIRSKNAEVK 
361:	KVAGPGVLSG FFAGVTEPII YGVNLPLKYP FYAGVVAGGI GGIIIAVGGN AFDAFVFPSV 
421:	MAFAATLSVG SFVAQLIGSS AALILGFVFT VVMFRKEQNV DKQETDTTPN VAAAASGTYV 
481:	PLAEIPDKVF SSGAMGDGFG IVPENGEIVS PVEGQLIAVQ KSGHAYGIRG DNGIEVLVHV 
541:	GIDTVKMAGE GFEILVARGD HVKVGQPLAK VDLNAVAEAG FDPTTAVIVT NSKKLEGLKF 
601:	TDVEGHVGAG DVVMRMEP