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4.A.2.1.13
The fructose-specific PTS Enzyme IIABC FruA (Araki et al., 2011).

Accession Number:Q0S1N2
Protein Name:Phosphotransferase system, fructose-specific
Length:700
Molecular Weight:70024.00
Species:Rhodococcus sp. (strain RHA1) [101510]
Number of TMSs:8
Substrate fructose

Cross database links:

eggNOG: COG1299
HEGENOM: HBG704192
Entrez Gene ID: 4224333   
Pfam: PF00359    PF02378    PF02302   
KEGG: rha:RHA1_ro0678   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phosphotransferase system

References (1)

[1] “The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.”  McLeod M.P.et.al.   17030794

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSHSTPDRDS GPQIISEDLI SLDTDLGASK EDVISALSRR LADAGRATEA DALRDAALAR 
61:	ESQSATGLPG GIAIPHCRSE AVVAASLGFA RLAPKVDFGA PDGPADLVFL IAAPEGAGAE 
121:	HMKLLSSLAR ALVRPAFVGA LRDAKTPAEI VTLVNDVLAP APAATPAAAA PAAAAAAAPA 
181:	AAAAVPAPKP EPVAPEKEPE PEVGPKHIVA VTACPTGIAH TYMAADSLVA AGERAGVVVH 
241:	VETQGSSGST PLAPGVIAGA SAVIFATDVG VKGKERFAGK PVVASGVKRA INEPDTMITE 
301:	ALRAGMNPSA AIVDAGSAGS AADEPAGSIG WGTHLRQVLL TGVSYMIPFV AAGGLLIALG 
361:	FLLGGYEISG PAEDIVLSNS LGQLPEGGLA TYLGAVLFQL GSLAFSFLVP ALAGYIAFAI 
421:	ADRPGLAPGF TAGAVAVFVG AGFIGGLVGG LIAGVVALWI SRIPVPQWLR GLMPVVIIPL 
481:	FATLIVGALM FLVLGRPLAS ITSGLTNWLN GLSGSSVIFL GIILGLMMCF DLGGPVNKAA 
541:	YAFAVAGLNV NDPASLRIMA AVMAAGMVPP LAMALASTVL RPSLFSEAER ENGKAAWLLG 
601:	SAFISEGAIP FAAADPLRVI PSMMAGGAVT GALIMAFDVT LSAPHGGIFV FFAIGNLLWF 
661:	LVALAAGVVV AALCVVGAKE FIKPGASDAE LDPDVATVAA