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4.A.2.1.4
The fructose porter, FruA (fructose-1-P forming IIABC) (Delobbe et al. 1975) FruA is 39% identical to 4.A.2.1.1). fructose can be metabolized to Fru-1-P via this system as well as Fru-6-P by another PTS system (Gay and Delobbe 1977).

Accession Number:P71012
Protein Name:Phosphotransferase system (PTS) fructose-specific enzyme IIABC component aka Fructose PTS IIABC
Length:635
Molecular Weight:67184.00
Species:Bacillus subtilis [1423]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate fructose

Cross database links:

HEGENOM: HBG704192
RefSeq: NP_389323.1   
Entrez Gene ID: 938757   
Pfam: PF00359    PF02378    PF02302   
BioCyc: SUBTI:BSU14400-MONOMER   
KEGG: bsu:BSU14400   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (1)

[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
Structure:
2R4Q     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKITELLTKH TIKLNIESKE KENVIDEMVT VLDKAGKLND RQAYKEAILN RESQSSTGIG 
61:	EGIAIPHAKT ASVINPAIAF GRSKDGVDYE SLDGQPAHLV FMIAATEGAN NTHLEALSRL 
121:	STLLMREEIR KQLLEAESED AIIDIINQHD KDDDEEEEEE EAAPAPAGKG KILAVTACPT 
181:	GIAHTFMAAD ALKEKAKELG VEIKVETNGS SGIKHKLTAQ EIEDAPAIIV AADKQVEMER 
241:	FKGKRVLQVP VTAGIRRPQE LIEKAMNQDA PIYQGSGGGS AASNDDEEAK GKSGSGIGNT 
301:	FYKHLMSGVS NMLPFVVGGG ILVAISFFWG IHSADPNDPS YNTFAAALNF IGGDNALKLI 
361:	VAVLAGFIAM SIADRPGFAP GMVGGFMATQ ANAGFLGGLI AGFLAGYVVI LLKKVFTFIP 
421:	QSLDGLKPVL IYPLFGIFIT GVLMQFVVNT PVAAFMNFLT NWLESLGTGN LVLMGIILGG 
481:	MMAIDMGGPL NKAAFTFGIA MIDAGNYAPH AAIMAGGMVP PLGIALATTI FRNKFTQRDR 
541:	EAGITCYFMG AAFVTEGAIP FAAADPLRVI PAAVVGAAVA GGLTEFFRVT LPAPHGGVFV 
601:	AFITNHPMLY LLSIVIGAVV MAIILGIVKK PVTEK