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4.A.2.1.7
The fructose inducible fructose/xylitol porter, FruI (Benchabane et al., 2002; Tanzer et al., 2006; Wen et al., 2001)

Accession Number:Q1LZ59
Protein Name:FruI
Length:655
Molecular Weight:68229.00
Species:Streptococcus mutans UA159 [210007]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Secreted1
Substrate fructose, Xylitol

Cross database links:

eggNOG: COG1299
RefSeq: NP_721281.1   
Entrez Gene ID: 1028238   
Pfam: PF00359    PF02378    PF02302   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (1)

[1] “Characterization of two operons that encode components of fructose-specific enzyme II of the sugar:phosphotransferase system of Streptococcus mutans.”  Wen Z.T.et.al.   11750824

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKIQDLLNKD VMLLDLQATT KEAAIDEMVS KLVEQGIVTD FDTFKAGIMN REVQTSTGLG 
61:	DGIAMPHSKN KAVKEATVLF AKSNKGVDYE ALDGEPVDLF FMIAAPDGAN DTHLAALAEL 
121:	SQYLLKDGFA DKLRQVTNPD DVINLFNATE EEKKEATPAA PVADSHDFLV AVTACTTGIA 
181:	HTYMAEEALK KQAAEMGVGI KVETNGASGV GNKLTADDIK RAKGVIIAAD KAVEMDRFNG 
241:	KPLISRPVAE GIKKPEELIN IILDGKAEAY VADNSDLSSE ASSSEKAGLG SAFYKHLMSG 
301:	VSQMLPFVIG GGIMIALSFL IDQFMGVPKS SLSHLGNYHE IAAIFNQVGN AAFGFMIPVF 
361:	AAYIAYSIAE KPGLVAGFVA GSMATTGLAF NKVAFFEFGE KASQASLTGI PSGFLGALAG 
421:	GFLAGGVILV LKKALAFVPR SLEGIKSILL YPLLGVLVTG FLMLFVNIPM AAINTALYNF 
481:	LGNLSGGSAV LLGLIVGGMM AIDMGGPFNK AAYVFGTSTL TAAALAKGGS VVMASVMAGG 
541:	MVPPLAVFVA TLLFKNKFTQ EEHDAGLTNI VMGLSFITEG AIPFGAGDPA RAIPSFIVGS 
601:	AVTGALVGLS GIKLMAPHGG IFVIALTSNP LLYLLYIAVG AVIAGILFGS LRKVR