TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*4.A.3.1.1









Lactose (Lac) porter
Bacteria
Firmicutes
Lactose (Lac) IICB-IIA complex of Staphylococcus aureus
IIA (LacF) (P02909)
IIBC (LacE) (P11162)
*4.A.3.1.2









Lactose PTS group translocator #1, IIA/IICB (Francl et al. 2012).

Bacteria
Firmicutes
Lactose PTS porter #1of Lactobacillus gasseri
*4.A.3.1.3









Lactose PTS group translocator #2, IIA/IICB (Francl et al. 2012).

Bacteria
Firmicutes
Lactose PTS porter #2 of Lactobacillus gasseri
*4.A.3.2.1









N,N'-diacetylchitobiose (Chb) porter (also transports cellobiose; Kachroo et al., 2007).
Bacteria
Proteobacteria
N,N'-diacetylchitobiose (Chb) IIC-IIB-IIA complex of E. coli
IIA (ChbA), spP17335
IIB (ChbB), spP17409
IIC (ChbC), spP17334
*4.A.3.2.2









Lichenan oligosaccharide (Lic) porter
Bacteria
Firmicutes
Lichenan oligosaccharide (Lic) IIC-IIB-IIA complex of Bacillus subtilis
IIA (LicA), spP46319
IIB (LicB), spP46318
IIC (LicC), spP46317
*4.A.3.2.3









N,N'-diacetylchitobiose porter, ChbABC

Bacteria
Spirochaetes
N,N'diacetylchitobiose (Chb) IIC-IIB-IIA complex of Borrelia burgdorferi
IIA (ChbA), AAC66323
IIB (ChbB), AAC66322
IIC (ChbC), AAC66324
*4.A.3.2.4









The cellobiose-specific (PtcA-PtcB-CelB) porter (Kowalczyk et al., 2008 ).

Bacteria
Firmicutes
PtcA-PtcB-CelB of Lactococcus lactis:
CelB (C)(Q9CJ32) PtcB (B)(Q9CIF0) PtcA (A)(Q9CIE9)
*4.A.3.2.5









The N,N' -diacetylchitobiose Enzyme II (Toratani et al., 2008) (>80% identical to the E. coli enzyme (4.A.3.2.1)).  The IIA protein is the Serratia glucose IIA which is nearly identical to the E. coli IIAGlc (Crr).

Bacteria
Proteobacteria
The N,N' -diacetylchitobiose Enzyme II of Serratia marcescens
IIA (ChbA) - Q8L3C4
IIB (ChbB) - Q8L3C3
IIC (ChbC) - Q8L3C2
*4.A.3.2.6









Glucosamine β(1→4) glucosamine (GlcN)2 (glucosamine dimer) transporter, VC1281-1283 (IIB; IIC; IIA, respectively) (Meibom et al., 2004)
Bacteria
Proteobacteria
(GlcN)2 transporter of Vibrio cholerae (IIA-IIB-IIC)
IIB (Q9KSH5)
IIA (Q9KSH3)
IIC (Q9KSH4)
*4.A.3.2.7









N,N'-diacetylchitobiose (cellobiose) PTS permease, CelABC (IIABC).  Essential for normal virulence and biofilm formation by K. pneumoniae which causes pyogenic liver abscesses (Wu et al. 2012).  88% identical to the diacetylchitobiose II (4.A.3.2.1) of E. coli.  These two proteins are probably orthologous. 

Bacteria
Proteobacteria
CelABC of Klebsiella pneumoniae
*4.A.3.2.8









N-, N'-diacetylchitobiose PTS permease, IIABCChb (Also called IIABCCel for cellbiose). The crystal structure of the 10 TMS IIC membrane component has been determined by x-ray crystallography (Cao et al. 2011).

Bacteria
Firmicutes
ChbIIABC of Bacillus cereus
ChbA (CelA); IIB (100 aas) (Q72XP9)
ChbB (CelB); IIC (433 aas) (Q72XQ0)
ChbC (CelC); IIA (106 aas) (Q72XQ1)
*4.A.3.2.9









PTS-type lactose transporter, IIC-IIB-IIA (Imai and Hall 1981; Hall et al. 1982). 

Bacteria
Proteobacteria
Lactose permease of Klebsiella pneumoniae
*4.A.3.2.10









Oligo β-(gluco)mannoside (derived from (gluco)mannan))-specific PTS transporter, GmuABC (YdhNMO). The glucomannan utilization operon (gmuBACDREFG, formerly ydhMNOPQRST) of Bacillus subtilis has been characterized (Sadaie et al. 2008). Transcription of the operon is induced by konjac glucomannan and requires the last mannanase gene (gmuG). Cellobiose and mannobiose, possible degradation products of glucomannan by GmuG, are strong inducers of transcription. An internal regulatory gene (gmuR) encodes a repressor of the operon, as disruption of this gene enhances transcription of the operon in the absence of inducers. The expression of the glucomannan utilizing operon is thus induced by degraded glucomannan products, and repressed by an internal repressor (Sadaie et al. 2008).

Bacteria
Firmicutes
GmuABC of Bacillus subtilis
GmuA, IIA, 110 aas, O05506
GmuB, IIB, 103 aas, O05505
GmuC, IIC, 422 aas and 10 TMSs, O05507