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4.C.1.1.11
Long-chain fatty acid transport protein 6 (FATP-6) (Fatty acid transport protein 6) (Fatty-acid-coenzyme A ligase, very long-chain 2) (Solute carrier family 27 member 6) (Very long-chain acyl-CoA synthetase homologue 1) (VLCSH1) (hVLCS-H1)

Accession Number:Q9Y2P4
Protein Name:Long-chain fatty acid transport protein 6
Length:619
Molecular Weight:70112.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate fatty acids

Cross database links:

Genevestigator: Q9Y2P4
eggNOG: COG0318
HEGENOM: HOG000044189
Entrez Gene ID: 28965   
Pfam: PF00501   
KEGG: hsa:28965   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0042383 C:sarcolemma
GO:0004467 F:long-chain fatty acid-CoA ligase activity
GO:0000166 F:nucleotide binding
GO:0031957 F:very long-chain fatty acid-CoA ligase activity
GO:0015909 P:long-chain fatty acid transport
GO:0055085 P:transmembrane transport
GO:0000038 P:very long-chain fatty acid metabolic process

References (3)

[1] “Characterization of a heart-specific fatty acid transport protein.”  Gimeno R.E.et.al.   12556534
[2] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLLSWLTVLG AGMVVLHFLQ KLLFPYFWDD FWFVLKVVLI IIRLKKYEKR GELVTVLDKF 
61:	LSHAKRQPRK PFIIYEGDIY TYQDVDKRSS RVAHVFLNHS SLKKGDTVAL LMSNEPDFVH 
121:	VWFGLAKLGC VVAFLNTNIR SNSLLNCIRA CGPRALVVGA DLLGTVEEIL PSLSENISVW 
181:	GMKDSVPQGV ISLKEKLSTS PDEPVPRSHH VVSLLKSTCL YIFTSGTTGL PKAAVISQLQ 
241:	VLRGSAVLWA FGCTAHDIVY ITLPLYHSSA AILGISGCVE LGATCVLKKK FSASQFWSDC 
301:	KKYDVTVFQY IGELCRYLCK QSKREGEKDH KVRLAIGNGI RSDVWREFLD RFGNIKVCEL 
361:	YAATESSISF MNYTGRIGAI GRTNLFYKLL STFDLIKYDF QKDEPMRNEQ GWCIHVKKGE 
421:	PGLLISRVNA KNPFFGYAGP YKHTKDKLLC DVFKKGDVYL NTGDLIVQDQ DNFLYFWDRT 
481:	GDTFRWKGEN VATTEVADVI GMLDFIQEAN VYGVAISGYE GRAGMASIIL KPNTSLDLEK 
541:	VYEQVVTFLP AYACPRFLRI QEKMEATGTF KLLKHQLVED GFNPLKISEP LYFMDNLKKS 
601:	YVLLTRELYD QIMLGEIKL