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4.C.1.1.12
Long-chain fatty acid transport protein 3 (FATP-3) (Fatty acid transport protein 3) (EC 6.2.1.-) (Solute carrier family 27 member 3) (Very long-chain acyl-CoA synthetase homologue 3) (VLCS-3)

Accession Number:Q5K4L6
Protein Name:Long-chain fatty acid transport protein 3
Length:730
Molecular Weight:78644.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Mitochondrion membrane1 / Multi-pass membrane protein2
Substrate fatty acids

Cross database links:

Genevestigator: Q5K4L6
eggNOG: COG0318
Entrez Gene ID: 11000   
Pfam: PF00501   
KEGG: hsa:11000   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0031966 C:mitochondrial membrane
GO:0004321 F:fatty-acyl-CoA synthase activity
GO:0016874 F:ligase activity
GO:0000166 F:nucleotide binding
GO:0006631 P:fatty acid metabolic process

References (4)

[1] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”  Clark H.F.et.al.   12975309
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGVCQRTRAP WKEKSQLERA ALGFRKGGSG MFASGWNQTV PIEEAGSMAA LLLLPLLLLL 
61:	PLLLLKLHLW PQLRWLPADL AFAVRALCCK RALRARALAA AAADPEGPEG GCSLAWRLAE 
121:	LAQQRAAHTF LIHGSRRFSY SEAERESNRA ARAFLRALGW DWGPDGGDSG EGSAGEGERA 
181:	APGAGDAAAG SGAEFAGGDG AARGGGAAAP LSPGATVALL LPAGPEFLWL WFGLAKAGLR 
241:	TAFVPTALRR GPLLHCLRSC GARALVLAPE FLESLEPDLP ALRAMGLHLW AAGPGTHPAG 
301:	ISDLLAEVSA EVDGPVPGYL SSPQSITDTC LYIFTSGTTG LPKAARISHL KILQCQGFYQ 
361:	LCGVHQEDVI YLALPLYHMS GSLLGIVGCM GIGATVVLKS KFSAGQFWED CQQHRVTVFQ 
421:	YIGELCRYLV NQPPSKAERG HKVRLAVGSG LRPDTWERFV RRFGPLQVLE TYGLTEGNVA 
481:	TINYTGQRGA VGRASWLYKH IFPFSLIRYD VTTGEPIRDP QGHCMATSPG EPGLLVAPVS 
541:	QQSPFLGYAG GPELAQGKLL KDVFRPGDVF FNTGDLLVCD DQGFLRFHDR TGDTFRWKGE 
601:	NVATTEVAEV FEALDFLQEV NVYGVTVPGH EGRAGMAALV LRPPHALDLM QLYTHVSENL 
661:	PPYARPRFLR LQESLATTET FKQQKVRMAN EGFDPSTLSD PLYVLDQAVG AYLPLTTARY 
721:	SALLAGNLRI