TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*5.A.2.1.1









Disulfide bond formation protein (disulfide oxidoreductase), DsbB
Bacteria
Proteobacteria
DsbB of E.coli (P0A6M2)
*5.A.2.1.2









The DsbI (223 aas and 4 TMSs in a 3 + 1 arrangement)/DsbL (222 aas and 1 N-terminal TMS) disulfide bond oxidoreductase/thio:disulfide interchange protein together form a dithiol oxidase system, acting on the periplasmic enzyme arylsulfate sulfotransferase, AssT (598 aas, 1 N-terminal TMS, Q8FDI4) which requires a disulfide bond for activity. The 3-d structure of DsbL at 1.55 Å resolution has been determined. DsbL is one of the most reactive oxidizing thioredoxin-like protein known (Grimshaw et al. 2008).  These three enzymes are encoded within a tricistronic operon.

Bacteria
Proteobacteria
DsbI/DsbL of E. coli