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5.B.1.2.1
NADPH oxido-reductase of 450 aas and 7 TMSs.  These proteins have been characterized in prokaryotes as well as eukaryotes (Hajjar et al. 2017).

Accession Number:Q9KN15
Protein Name:VCA0151
Length:450
Molecular Weight:51143.00
Species:Vibrio cholerae [666]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Electrons

Cross database links:

HEGENOM: HBG470491
RefSeq: NP_232551.1   
Entrez Gene ID: 2612539   
Pfam: PF00970    PF01794    PF00175   
KEGG: vch:VCA0151   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0009055 F:electron carrier activity
GO:0050660 F:FAD binding
GO:0005506 F:iron ion binding
GO:0016491 F:oxidoreductase activity
GO:0055114 P:oxidation reduction

References (1)

[1] “DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.”  Heidelberg J.F.et.al.   10952301

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIKWNWVMSR VKYTLWVVVG IVTLLWVQAE PTLFGSTNLF QWRSGLVQFS GILALMLMSL 
61:	AMLLALRLPL IEQWTQGIDK GYRIHKWLGI SALLLGIFHW LAYHLPKWLI SLELLTKPAR 
121:	LNGSGPNSNL SGLALWLKEA KPLAMEIGEW GFYALIVLLV VSLWSAIKYK PFRLTHRLMA 
181:	VVYLLIALHS VILLKKAYWG EPIYWLTMLF IVVGSWAACY SLLGLVGRQS RYPAHVKAFH 
241:	YCPNSQTLDL TIQLDKPWLG HKAGQFAYLK FAGEEPHPFT IACAHQGSQL RFLIKELGDF 
301:	TTGLHQRLQN GKSLEVEGPY GKFDFSTQQP QIWIGGGVGI APFMAGLDWL MRERAHPPVH 
361:	LFFCCHQIDP DLCAELRHKA QLAGVSLTII DSSVDPHLSA DDIARRCGDL SRFEIYFCGP 
421:	IAFSNSLKKA LKPYQVDLSR QFHEEQFVMR