TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*5.B.2.1.1









Cytochrome b561 with an N-terminal cellobiose dehydrogenase (CDH)-like domain and a C-terminal cytb561 - FRRS1-like domain, both containing heme binding sites (Bérczi and Zimányi 2014).

Eukaryota
Metazoa
Cytb561 of Bos taurus (P10897)
*5.B.2.1.2









Tumor suppressor (Tsp10 pending protein)
Eukaryota
Metazoa
Tsp10 of Mus musculus (NP_062694)
*5.B.2.1.3









Duodenyl cytochrome b ferrireductase, Dcytb. Duodenyl L-Ascorbate (in):Fe3+ iron chelate (out) oxidoreduclase. Present in duodenal enterocyte brush boarder membranes (isoform 1); reduces dietary Fe3+ to Fe2+ to facilitate its transport into the mucosal cell. Binds two hemes non-covalently. Induced by iron deficiency. Also expressed in erythrocytes and respiratory epithelia (Lane and Lawen, 2009).  

Eukaryota
Metazoa
Duodenyl cytochrome b reductase of Homo sapiens (Q53TN4)
*5.B.2.1.4









Secretory vesicle-specific (chromafin granule) cytochrome b561 (isoform 2)

Eukaryota
Metazoa
Cytochrome b561 of Homo sapiens (P49447)
*5.B.2.1.5









The Lysosomal ascorbate:ferric chelate oxidoreductase, Cytochrome b561 (isoform 3).

Eukaryota
Metazoa
Lysosomal cytochrome b561 of Homo sapiens (Q6P1H1)
*5.B.2.1.6









Ascorbate-specific transmembrane electron transporter 1 (Cytochrome b561-1; Zmb561)

Eukaryota
Viridiplantae
ZCYB of Zea mays
*5.B.2.1.7









Cytochrome b561 ferric reductase (Glanfield et al. 2010).

Eukaryota
Metazoa
Cyt b561 of Schistosoma japonicum
*5.B.2.2.1









Ferric chelate reductase

Eukaryota
Viridiplantae
Ferric chelate reductase of Medicago truncatula
*5.B.2.2.2









Cytochrome b561 ferric reductase with N-terminal DOMON-related domain (for heme or sugar binding).

Eukaryota
Viridiplantae
Ferric reductase of Arabidopsis thaliana
*5.B.2.2.3









Ferric-chelate reductase 1. Involved in neurotransmitter synthesis and dietary iron uptake. (Picco et al. 2014).

Eukaryota
Metazoa
Ferric-chelate reductase 1 homologue of Drosophila melanogaster
*5.B.2.2.4









Ferric chelate reductase homologue (N-terminus; 5 TMSs; TC# 5.B.2; may reduce Cu2+ to Cu+) fused to a Ctr copper transporter (C-terminus; 3 TMSs; Ctr family, TC# 1.A.56).

Eukaryota
Bangiophyceae
Ctr fusion protein of Galdieria sulphuraria
*5.B.2.2.5









Uncharacterized protein of 535 aas and 5 C-terminal TMSs with an N-terminal DOMON domain and a C-terminal cytochrome b561 domain.

Eukaryota
Viridiplantae
UP of Chlamydomonas reinhardtii
*5.B.2.3.1









Uncharacterized protein of 403 aas and 6 TMSs in a 1 (N-termina) plus 5 TMS arrangement.

Eukaryota
Fungi
UP of Setosphaeria turcica (Northern leaf blight fungus) (Exserohilum turcicum)
*5.B.2.3.2









Uncharacterized protein with an N-terminal TMS followed by a heme binding cytochrome domain of fungal cellubiose dehydrogenases and a C-terminal Cytochrome b-561 / ferric reductase 5 TMS transmembrane domain of 453 aas.

Eukaryota
Fungi
UP of Hypocrea virens (Gliocladium virens) (Trichoderma virens)
*5.B.2.3.3









Uncharacterized putative cellobiose dehydrogenase of 476 aas and 6 (1 + 5) TMSs. These 5 TMSs may be homologous to those of the CBP family (9.B.306), but homology has not been established.

Eukaryota
Fungi
UP of Ophiocordyceps sinensis