TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*8.A.1.1.1









Membrane Fusion Protein, EmrA, that function with MFS multidrug exporter, EmrB (Nishino and Yamaguchi 2001).

Bacteria
Proteobacteria
EmrA of E. coli
*8.A.1.1.2









The MFP cluster 1 protein, FarA (efflux of antimicrobial long chain fatty acids (Lee et al., 2006); functions with MFS carrier, FarB (TC# 2.A.1.3.20))
Bacteria
Proteobacteria
FarA of Neisseria gonorrhoeae (Q9RQ30)
*8.A.1.1.3









MdtN; acts with MdtO (TC# 2.A.85.6.1) and MdtP (TC# 1.B.17.3.9) (Sulavik et al., 2001).

Bacteria
Proteobacteria
MdtN of E. coli (B1LPP9)
*8.A.1.1.4









Membrane fusion protein, YiaV

Bacteria
Proteobacteria
YiaV of E. coli
*8.A.1.2.1









CzcB of MFP cluster 2 (functions with RND porter CzcA, TC# 1.A.6.1.2 and CzcC, TC# 1.B.17.2.1).

Bacteria
Proteobacteria
CzcB of Alcaligenes eutrophus
*8.A.1.2.2









Uncharacterized MFP of 314aas and 1 TMS.

Bacteria
Proteobacteria
MFP of Bdellovibrio exovorus
*8.A.1.3.1









MFP cluster 3 (function with ABC porters) (Pimenta et al., 2005)
Bacteria
Proteobacteria
HlyD of E. coli
*8.A.1.3.2









MFP (cluster3). CyaD (functions with CyaB (TC# 3.A.1.109.2)) (Glaser et al., 1988)
Bacteria
Proteobacteria
CyaD of Bordetella pertussis (P11091)
*8.A.1.3.3









The MFP, EexE of cluster 3 (functions with the ABC porter EexD, (TC# 3.A.1.110.10) and OMF EexF (TC# 1.b.17.1.3)) (Gimmestad et al., 2006

).

Bacteria
Proteobacteria
EexE of Azotobacter vinelandii (C1DS85)
*8.A.1.3.4









Leukotoxin export MFP protein of 457 aas, TdcA (Guthmiller et al. 1995).  Functions with the ABC exporter, LtxB (TC# 3.A.109.8) and the TolC-like OMF protein, TdeA (TC# 1.B.17.3.11).

Bacteria
Proteobacteria
Leukotoxin export MFP of Aggregatibacter (Actinobacillus; Haemophilus) actinomycetemcomitans
*8.A.1.3.5









Uncharacterized MFP of 346 aas and 1 N-terminal TMS. Possibly functions with an RND pump.

Bacteria
Proteobacteria
UP of Parvularcula oceani
*8.A.1.4.1









Mesenterecin Y105 (bacteriocin) secresion accessory protein, MesE  of 457 aas (cluster 4). Functions with MesD; TC#3.A.1.112.8.

Bacteria
Firmicutes
MesE of Leuconostoc mesenteroides
*8.A.1.4.2









Competence factor transport accessory protein, ComB
Bacteria
Firmicutes
ComB of Streptococcus pneumoniae
*8.A.1.5.1









Open reading frame, Orf2
Bacteria
Firmicutes
Orf2 of Lactobacillus gasseri
*8.A.1.6.1









Acridine efflux pump constituent, AcrA
Bacteria
Proteobacteria
AcrA of E. coli (P0AE06)
*8.A.1.6.2









The multidrug efflux pump constituent, MdtA [may form a complex with MdtB and MdtC (2.A.6.2.12), both RND proteins. All three proteins appear to be required for resistance (Baranova and Nikaido, 2002).

Bacteria
Proteobacteria
MdtA of E. coli (P76397)
*8.A.1.6.3









Multidrug resistance protein MdtE (YhiU).  Functions with MdtF (TC# 8.A.1.6.3).

Bacteria
Proteobacteria
MdtE of E. coli
*8.A.1.6.4









Cation translocating membrane fusion protein of 295 aas

Bacteria
Planctomycetes
MFP of Rhodopirellula baltica
*8.A.1.7.1









MFP, AaeA, that functions with AaeB, a γ-hydroxybenzoate efflux pump, a member of the Aromatic Acid Exporter Family (TC# 2.A.85) (Van Dyk et al., 2004).
Bacteria
Proteobacteria
AaeA of Escherichia coli (P46482)