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8.A.1.1.3
MdtN; acts with MdtO (TC# 2.A.85.6.1) and MdtP (TC# 1.B.17.3.9) (Sulavik et al., 2001).

Accession Number:B1LPP9
Protein Name:Multidrug resistance protein MdtN
Length:343
Molecular Weight:36922.00
Species:Escherichia coli (strain SMS-3-5 / SECEC) [439855]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

HEGENOM: HBG624965
RefSeq: YP_001746474.1   
Entrez Gene ID: 6145357   
Pfam: PF00529   
KEGG: ecm:EcSMS35_454   

Gene Ontology

GO:0009276 C:Gram-negative-bacterium-type cell wall
GO:0016020 C:membrane
GO:0015238 F:drug transmembrane transporter activity
GO:0008565 F:protein transporter activity
GO:0006855 P:drug transmembrane transport
GO:0009306 P:protein secretion

References (1)

[1] “Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5.”  Fricke W.F.et.al.   18708504

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MESTPKKAPR SKFPALLVVA LALVALVFVI WRVDSAPSTN DAYASADTID VVPEVSGRIV 
61:	ELAVTDNQAV KQGDLLFRID PRPYEANLAK AEASLAALDK QIMLTQRSVD AQQFGADSVN 
121:	ATVEKARAAA KQATDTLRRT EPLLKEGFVS AEDVDRARTA QRAAEADLNA VLLQAQSAAS 
181:	AVSGVDALVA QRAAVEADIA LTKLHLEMAT VRAPFDGRVI SLKTSVGQFA SAMRPIFTLI 
241:	DTRHWYVIAN FRETDLKNIR SGTPATIRLM SDSGKTFEGK VDSIGYGVLP DDGGLVLGGL 
301:	PKVSRSINWV RVAQRFPVKI MVEKPDPEMF RIGASAVANL EPQ