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8.A.1.3.2
MFP (cluster3). CyaD (functions with CyaB (TC# 3.A.1.109.2)) (Glaser et al., 1988)

Accession Number:P11091
Protein Name:CyaD
Length:440
Molecular Weight:48054.00
Species:Bordetella pertussis [520]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Single-pass membrane protein2
Substrate NONE

Cross database links:

HEGENOM: HBG490717
RefSeq: NP_879580.1   
Entrez Gene ID: 2664600   
Pfam: PF00529   
BioCyc: BPER257313:BP0762-MONOMER   
KEGG: bpe:BP0762   

Gene Ontology

GO:0009276 C:Gram-negative-bacterium-type cell wall
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008565 F:protein transporter activity
GO:0019835 P:cytolysis
GO:0019836 P:hemolysis by symbiont of host erythrocytes
GO:0009306 P:protein secretion

References (2)

[1] “Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis.”  Glaser P.et.al.   2905265
[2] “Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.”  Parkhill J.et.al.   12910271

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRRALRELAA RHGRVLAASW RQRHRRPAGW FDPVETEFLP SALSLQERPI SPTARWLARI 
61:	LMALAAGALV WSVVGKTEIV VHAAGKVVPV GQSKIIAASE TGRVARVLVA DNSRVAAGDV 
121:	LLRLDAGVTE AEERKWRVQA AQARQDEARS RAMIRALDTG RAPVLAELPA DPGMMAAQSY 
181:	LDSQYADYQA QLRSIEAAIA TYRRELGLVT QIAHAHRGLR RDGDVSQQAY LEKEQARMTL 
241:	EGRLRQSEAQ RAALQTQTRR QAFETLVLAR KLAAQAEQEI ARTSAQRSRL VLTAPVDGVV 
301:	QQLVALTEGT AVAATQPLMM VVPSGAGIQV QAQLDSKDIG FVRAGAPATV KVGAYDYTKY 
361:	GTLEGKVLYV SPDTVVDDRQ QHSYRVTIAL AHPALEVDGK PRLLKEGMAV QADIRTGSRR 
421:	LIEYLLSPVA RHAGESLGER