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8.A.100.  The The Protein-Serine O-Palmitoleoyltransferase Porcupine (PS-PP) Family 

The protein, porcupine, is a  palmiteoyl transferase, known to acylate regulatory proteins such as Wnt.  It also regulates certain channel proteins.  For example it regulates the AMPA/TARP complex in a TARP-dependent manner (Kato and Witkin 2018).

References associated with 8.A.100 family:

Caricasole, A., T. Ferraro, J.M. Rimland, and G.C. Terstappen. (2002). Molecular cloning and initial characterization of the MG61/PORC gene, the human homologue of the Drosophila segment polarity gene Porcupine. Gene 288: 147-157. 12034504
Coombs, G.S., J. Yu, C.A. Canning, C.A. Veltri, T.M. Covey, J.K. Cheong, V. Utomo, N. Banerjee, Z.H. Zhang, R.C. Jadulco, G.P. Concepcion, T.S. Bugni, M.K. Harper, I. Mihalek, C.M. Jones, C.M. Ireland, and D.M. Virshup. (2010). WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification. J Cell Sci 123: 3357-3367. 20826466
Gao, X. and R.N. Hannoush. (2014). Single-cell imaging of Wnt palmitoylation by the acyltransferase porcupine. Nat Chem Biol 10: 61-68. 24292069
Herr, P. and K. Basler. (2012). Porcupine-mediated lipidation is required for Wnt recognition by Wls. Dev Biol 361: 392-402. 22108505
Kato, A.S. and J.M. Witkin. (2018). Auxiliary subunits of AMPA receptors: The discovery of a forebrain-selective antagonist, LY3130481/CERC-611. Biochem Pharmacol 147: 191-200. 28987594