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8.A.109.1.1
The ER junction-forming protein, Lunapark, LNP1 of 278 aas and possibly 2 N-terminal TMSs or 4 TMSs in a 2 + 2 arrangement with two N-terminal and 2 more C-terminal (Chen et al. 2012).  LNP1 aids in membrane fusion and maintenance of the endoplasmic reticulum (Casey et al. 2015). Works in conjunction with the ER shaping proteins (reticulons RTN1 and RTN2 (TC# 8.A.102), YOP1), and in antagonism to SEY1 to maintain the network in a dynamic equilibrium. May counterbalance SEY1-directed polygon formation by promoting polygon loss through ring closure (Chen et al. 2012).

Accession Number:P38878
Protein Name:Endoplasmic reticulum junction formation protein lunapark
Length:278
Molecular Weight:32063.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate

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FASTA formatted sequence
1:	MFSALGKWVR GSRNDKDFVT KYTADLSQIT SQIHQLDVAL KKSQSILSQW QSNLTFYGIA 
61:	LTVLALSYTY WEYHGYRPYL VVTALLCIGS LILFKWALTK LYAFYNNNRL RKLAKLRAIH 
121:	QKKLEKLKEE THYNATSSII QRFSSGEDQN DDAMVLLDDE LNAKYQELNN LKTELEKFKK 
181:	ESHVKGLKKE DSDAWFDKII SVLAGGNELD STSSLSPFKK IICPQCHWKS NCYRLASKPI 
241:	IFICPHCNHK IDEVKEREDA IEAKQPAQPS QSEKEKTK