TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*8.A.113.1.1









TMEM150c/Tentonin 3 of 249 aas and 6 TMSs.  According to Anderson et al. 2018, it reglulates other channels such as Piezo 1 and Piezo 2. According to Hong et al. 2017, it has inherent channel activity.

Eukaryota
Metazoa
TMEM150c of Homo sapiens
*8.A.113.1.2









TMEM150a of 271 aas and 6 TMSs.  Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (Chung et al. 2015). Acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns4P) synthesis (Chung et al. 2015). May also play a role in fasting-induced catabolism.

Eukaryota
Metazoa
TMEM150a of Homo sapiens
*8.A.113.1.3









TMEM150b of 233 aas and 6 TMSs.  Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux. Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner (Mrschtik et al. 2015). May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival.

Eukaryota
Metazoa
TMEM150b of Homo sapiens
*8.A.113.1.4









Uncharacterized TMEM150 homologue of 252 aas and 6 TMSs.

Eukaryota
Metazoa
UP of Schistosoma japonicum (Blood fluke)
*8.A.113.1.5









Uncharacterized DNA damage-regulated autophagy modulator protein 2 of 243 aas and 6 TMSs.

Eukaryota
Metazoa
UP of Anoplophora glabripennis (Asian longhorned beetle)
*8.A.113.1.6









Uncharacterized TMEM150b-like protein of 251 aas and 6 TMSs.

Eukaryota
Metazoa
UP of Branchiostoma belcheri (Belcher's lancelet) Isolated from sea water.
*8.A.113.1.7









Uncharacterized protein of 268 aas and 6 TMSs.

Eukaryota
Metazoa
UP of Pristionchus pacificus (Parasitic nematode)