TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


8.A.114.1.2
Huntington-interacting Protein 14, HIP14. Eukaryotic divalent cation transporter (Quamme, 2009)

Accession Number:Q9VUW9
Protein Name:Huntingtin-interacting protein 14
Length:637
Molecular Weight:71299.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

eggNOG: inNOG05098
RefSeq: NP_648824.1   
Entrez Gene ID: 39747   
Pfam: PF00023    PF01529   
KEGG: dme:Dmel_CG6017   

Gene Ontology

GO:0005794 C:Golgi apparatus
GO:0008021 C:synaptic vesicle
GO:0005515 F:protein binding
GO:0008270 F:zinc ion binding
GO:0016079 P:synaptic vesicle exocytosis

References (2)

[1] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572
[2] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MYQSACQAAT TGSCVPGTGQ QPDNERQSAL IAQQPPTAPV EPDYSGFDIV KATQYGAIAR 
61:	VRELVESGWD VNQPDSETVT LLHWAAINNR RDIIRYFLEK GATVDAVGGE LNATPLHWAT 
121:	RQGHLGAVVL LMAAGADPRI RDAEGCSCIH IAAQFAHTAL VAYFIAKGVD PDLQDRGGMT 
181:	ALMWAAWKVC ALDPVRLLLT LGANPAMVDY THGNTALHWA ILARNATAIS TLVLKSKASL 
241:	DVPNLRGETP LSMLESQTGA IWIGAKVMDR VKEAALTSQQ RRSLLSKLRH DKRLRWWSMV 
301:	ACPFTAFYLA GIVFTVNTLY IIKFFLLGCL YSIFHTIGKA LFDEHLMALL PLSVYLATKA 
361:	WFYVTWLMYI DDAVSFTATV CFLISSLLLW VCFLKSWKGD PGIIRPTREQ RFKTIIELSE 
421:	RGGIGFEPAS FCSGCLVRRP IRSKHCSVCD RCVARFDHHC PWVGNCIGLK NHSYFMGFLW 
481:	MLLIMCAWML YGGSKYYVNQ CNVRFDDFLG AMRAIGNCDA WVGWVMGNAL LHMSWVILLT 
541:	ICQTYQVICL GMTTNERMNR GRYRHFQAKG GHSPFTRGPI QNLVDFLECS CFGLVQPKRV 
601:	DWMNYYDYDA QTHQTIEKEP LLSVDCPDGM AGDHQYV