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8.A.114.1.6
Palmitoyltransferase ZDHHC20 of 365 aas and 4 TMSs in a 2 + 2 TMS arrangement.  It catalyzes palmitoylation of Cys residues in target proteins (Runkle et al. 2016). It has a preference for acyl-CoA with C16 fatty acid chains but can also utilize acyl-CoA with C14 and C18 fatty acid chains (Rana et al. 2018). It derivatizes the IFITM3 protein (TC# 8.A.58.1.3) which has anti-viral activity and makes physical contact with the V-ATPase in endosomes which is required for the function of this ATPase (McMichael et al. 2017).  

Accession Number:Q5W0Z9
Protein Name:Palmitoyltransferase ZDHHC20
Length:365
Molecular Weight:42278.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAPWTLWRCC QRVVGWVPVL FITFVVVWSY YAYVVELCVF TIFGNEENGK TVVYLVAFHL 
61:	FFVMFVWSYW MTIFTSPASP SKEFYLSNSE KERYEKEFSQ ERQQEILRRA ARALPIYTTS 
121:	ASKTIRYCEK CQLIKPDRAH HCSACDSCIL KMDHHCPWVN NCVGFSNYKF FLLFLLYSLL 
181:	YCLFVAATVL EYFIKFWTNE LTDTRAKFHV LFLFFVSAMF FISVLSLFSY HCWLVGKNRT 
241:	TIESFRAPTF SYGPDGNGFS LGCSKNWRQV FGDEKKYWLL PIFSSLGDGC SFPTRLVGMD 
301:	PEQASVTNQN EYARSSGSNQ PFPIKPLSES KNRLLDSESQ WLENGAEEGI VKSGTNNHVT 
361:	VAIEN