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8.A.14.1.1
Sloβ auxiliary subunit

Accession Number:Q9JIN6
Protein Name:Slo Beta Subunit aka KCNMB4
Length:210
Molecular Weight:23857.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: Q9JIN6
HEGENOM: HBG716488
RefSeq: NP_067427.1   
Entrez Gene ID: 58802   
Pfam: PF03185   
KEGG: mmu:58802   

Gene Ontology

GO:0008076 C:voltage-gated potassium channel complex
GO:0015269 F:calcium-activated potassium channel activity
GO:0005513 P:detection of calcium ion
GO:0006813 P:potassium ion transport
GO:0019228 P:regulation of action potential in neuron

References (2)

[1] “A novel nervous system beta subunit that downregulates human large conductance calcium-dependent potassium channels.”  Weiger T.M.et.al.   10804197
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MAKLRVSYEY TEAEDKSIRL GLFLIVSGIL SLFIFGFCWL SPALQDLQAT AANCTVLSVQ 
61:	QIGEVFECTF TCGTDCRGTS QYPCVQVYVN NSESNSRALL HSDQHQLLTN PKCSYIPPCK 
121:	RENQKNSESV MNWQQYWKDE IGSQPFTCYF NQHQRPEDVL LQRTHDEIAL LHCFLWPVVA 
181:	FVVGVLIVVL TICAKSLAVK AEAMKKRKFS