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8.A.16.1.1
Calcium channel γ1-subunit, CACNG1

Accession Number:Q06432
Protein Name:CACNG1 aka CACNLG
Length:222
Molecular Weight:25028.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: Q06432
eggNOG: prNOG10533
HEGENOM: HBG755243
RefSeq: NP_000718.1   
Entrez Gene ID: 786   
Pfam: PF00822   
Drugbank: Drugbank Link   
OMIM: 114209  gene
KEGG: hsa:786   

Gene Ontology

GO:0005891 C:voltage-gated calcium channel complex
GO:0015270 F:dihydropyridine-sensitive calcium channel a...
GO:0006816 P:calcium ion transport
GO:0006936 P:muscle contraction

References (4)

[1] “Molecular characterization of the gene encoding the gamma subunit of the human skeletal muscle 1,4-dihydropyridine-sensitive Ca2+ channel (CACNLG), cDNA sequence, gene structure, and chromosomal location.”  Powers P.A.et.al.   8387489
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Localization of the gamma-subunit of the skeletal muscle L-type voltage-dependent calcium channel gene (CACNLG) to human chromosome band 17q24 by in situ hybridization and identification of a polymorphic repetitive DNA sequence at the gene locus.”  Iles D.E.et.al.   8404045

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSQTKMLKVR VTLFCILAGI VLAMTAVVTD HWAVLSPHME HHNTTCEAAH FGLWRICTKR 
61:	IPMDDSKTCG PITLPGEKNC SYFRHFNPGE SSEIFEFTTQ KEYSISAAAI AIFSLGFIIL 
121:	GSLCVLLSLG KKRDYLLRPA SMFYAFAGLC ILVSVEVMRQ SVKRMIDSED TVWIEYYYSW 
181:	SFACACAAFI LLFLGGLALL LFSLPRMPRN PWESCMDAEP EH