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8.A.16.2.12
TARP Cacng2a (Stargazin homologue) of 324 aas.  Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), promoting their targeting to the cell membrane and synapses and modulating their gating properties by slowing their rates of activation, deactivation and desensitization. Regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (Roy et al. 2016).

Accession Number:Q6PFS3
Protein Name:Voltage-dependent calcium channel gamma subunit
Length:324
Molecular Weight:35888.00
Species:Danio rerio (Zebrafish) [7955]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGVFDRGVQM LLTTVGAFAA FSLMTIAVGT DYWLYSRGVC KIKTNNENET SKKNEEVMTH 
61:	SGLWRTCCLE GNFKGLCKQI DHFPEDTDYE ADASEYFLRA VRASSIFPIL SVILLFMGGL 
121:	CIAASEFYKS RHNIILSAGI LFVSAGLSNI IGMIVYISAN AGDPSKSDSK KNSYSYGWSF 
181:	YFGALSFIMA EMVGVLAVHM FIDRHRELRA GARAADYLQG SAITRIPSYR YRYRRRSRSS 
241:	SRSTDPSHSR DASPVGLKGF GALPSTEISM YTLTRGGDTL KGGHGTPTAT YNSERDHNFL 
301:	QVHNCIQKDL KDSSNTANRR TTPV