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8.A.16.2.3
Voltage-dependent Ca2+ channel γ4 subunit, CACNG4

Accession Number:Q9UBN1
Protein Name:CACNG4
Length:327
Molecular Weight:36579.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: Q9UBN1
HEGENOM: HBG564649
RefSeq: NP_055220.1   
Entrez Gene ID: 27092   
Pfam: PF00822   
OMIM: 606404  gene
KEGG: hsa:27092   

Gene Ontology

GO:0030666 C:endocytic vesicle membrane
GO:0005887 C:integral to plasma membrane
GO:0005245 F:voltage-gated calcium channel activity
GO:0006816 P:calcium ion transport

References (3)

[1] “Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.”  Burgess D.L.et.al.   10613843
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVRCDRGLQM LLTTAGAFAA FSLMAIAIGT DYWLYSSAHI CNGTNLTMDD GPPPRRARGD 
61:	LTHSGLWRVC CIEGIYKGHC FRINHFPEDN DYDHDSSEYL LRIVRASSVF PILSTILLLL 
121:	GGLCIGAGRI YSRKNNIVLS AGILFVAAGL SNIIGIIVYI SSNTGDPSDK RDEDKKNHYN 
181:	YGWSFYFGAL SFIVAETVGV LAVNIYIEKN KELRFKTKRE FLKASSSSPY ARMPSYRYRR 
241:	RRSRSSSRST EASPSRDVSP MGLKITGAIP MGELSMYTLS REPLKVTTAA SYSPDQEASF 
301:	LQVHDFFQQD LKEGFHVSML NRRTTPV