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8.A.16.2.5
Voltage dependent Ca2+ channel γ7 (γ-7) subunit, CACNG7 or TARP γ7.  Enhances synaptic expression and channel activity of Ca2+ permeable AMPA receptors (TC#1.A.10.1.1) (Studniarczyk et al. 2013; Kato et al. 2007).

Accession Number:P62955
Protein Name:CACNG7
Length:275
Molecular Weight:31003.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: P62955
eggNOG: prNOG15309
HEGENOM: HBG446234
RefSeq: NP_114102.2   
Entrez Gene ID: 59284   
Pfam: PF00822   
OMIM: 606899  gene
KEGG: hsa:59284   

Gene Ontology

GO:0005891 C:voltage-gated calcium channel complex
GO:0005245 F:voltage-gated calcium channel activity
GO:0006816 P:calcium ion transport

References (5)

[1] “A cluster of three novel Ca(2+) channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.”  Burgess D.L.et.al.   11170751
[2] “Calcium channel gamma subunits provide insights into the evolution of this gene family.”  Chu P.-J.et.al.   11738816
[3] “The novel product of a five-exon stargazin-related gene abolishes CaV2.2 calcium channel expression.”  Moss F.J.et.al.   11927536
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[5] “Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling.”  Wang Y.et.al.   17053785

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSHCSSRALT LLSSVFGACG LLLVGIAVST DYWLYMEEGT VLPQNQTTEV KMALHAGLWR 
61:	VCFFAGREKG RCVASEYFLE PEINLVTENT ENILKTVRTA TPFPMVSLFL VFTAFVISNI 
121:	GHIRPQRTIL AFVSGIFFIL SGLSLVVGLV LYISSINDEV MNRPSSSEQY FHYRYGWSFA 
181:	FAASSFLLKE GAGVMSVYLF TKRYAEEEMY RPHPAFYRPR LSDCSDYSGQ FLQPEAWRRG 
241:	RSPSDISSDV SIQMTQNYPP AIKYPDHLHI STSPC