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8.A.16.2.8
Transmembrane protein 178

Accession Number:Q8NBL3
Protein Name:Transmembrane protein 178
Length:297
Molecular Weight:33019.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: Q8NBL3 Q8NBL3
eggNOG: NOG42792 NOG42792
HEGENOM: HOG000063712 HOG000063712
Entrez Gene ID: 130733    130733   
KEGG: hsa:130733    hsa:130733   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0016021 C:integral to membrane

References (8)

[1] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”  Clark H.F.et.al.   12975309
[2] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”  Otsuki T.et.al.   16303743
[3] “Generation and annotation of the DNA sequences of human chromosomes 2 and 4.”  Hillier L.W.et.al.   15815621
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[5] “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.”  Clark H.F.et.al.   12975309
[6] “Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.”  Otsuki T.et.al.   16303743
[7] “Generation and annotation of the DNA sequences of human chromosomes 2 and 4.”  Hillier L.W.et.al.   15815621
[8] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEPRALVTAL SLGLSLCSLG LLVTAIFTDH WYETDPRRHK ESCERSRAGA DPPDQKNRLM 
61:	PLSHLPLRDS PPLGRRLLPG GPGRADPESW RSLLGLGGLD AECGRPLFAT YSGLWRKCYF 
121:	LGIDRDIDTL ILKGIAQRCT AIKYHFSQPI RLRNIPFNLT KTIQQDEWHL LHLRRITAGF 
181:	LGMAVAVLLC GCIVATVSFF WEESLTQHVA GLLFLMTGIF CTISLCTYAA SISYDLNRLP 
241:	KLIYSLPADV EHGYSWSIFC AWCSLGFIVA AGGLCIAYPF ISRTKIAQLK SGRDSTV