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8.A.16.3.1
Tetrameric tetraspanin MP20 (4 TMS scaffold protein; Gonen et al., 2007)

Accession Number:P54825
Protein Name:Tetraspanin MP20
Length:173
Molecular Weight:19637.00
Species:Rattus norvegicus (Rat) [10116]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

Genevestigator: P54825
eggNOG: roNOG16649
RefSeq: NP_446223.1   
Entrez Gene ID: 114903   
Pfam: PF00822   
KEGG: rno:114903   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0031982 C:vesicle
GO:0005212 F:structural constituent of eye lens

References (3)

[1] “Cloning and expression of a major rat lens membrane protein, MP20.”  Kumar N.M.et.al.   7679355
[2] “The human lens fiber-cell intrinsic membrane protein MP19 gene: isolation and sequence analysis.”  Church R.L.et.al.   8137630
[3] “Identification of an 18,000-dalton protein in mammalian lens fiber cell membranes.”  Louis C.F.et.al.   2584203

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MYSFMGGGLF CAWVGTILLV VATATDHWMQ YRLSGSFAHQ GLWRYCLGNK CFLQTESIAY 
61:	WNATRAFMIL SALCATSGII MGVLAFAQQS TFTRLSRPFS AGIMFFASTL FVLLALAIYT 
121:	GVTVSFLGRR FGDWRFSWSY ILGWVALLMT FFAGIFYMCA YRMHECRRLS TPR