TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*8.A.21.1.1









Erythrocyte stomatin (Band 7) (Similar to Mechanosensory protein Mec2 (1.A.6.2.2))

Eukaryota
Metazoa
Stomatin of Homo sapiens (P27105)
*8.A.21.1.2









Podocin of 383 aas and 1 TMS.  Expressed exclusively in the slit-diaphragm of podocytes.  Mutations lead to steroid resistance followed by renal disease (Mulukala et al. 2016).

Podocin of Homo sapiens
*8.A.21.1.3









Stomatin-like protein 3, STROML3 of 291 aas and 2 TMSs.  Functions in the regulation of ASIC channels in mobile vesicles in sensory neurons (Lapatsina et al. 2012).

Eukaryota
Metazoa
STROML3 of Homo sapiens
*8.A.21.2.1









Stomatin homologue. Cleavage of this protein by a protease encoded within the same operon as the stomatin has been reported to open an ion channel (Yokoyama and Matsui, 2005).

Archaea
Euryarchaeota
Stomatin homologue and its protease of Pyrococcus horikoshii
Stomatin homologue (O59180)
Protease (NP_143370)
*8.A.21.2.2









QmcA protein (bacterial homologue) of 305 aas and 1 TMS (N-terminal).  May play a role in the quality control of integral membrane proteins. There is no evidence that it plays a role in transport.

Bacteria
Proteobacteria
QmcA of E. coli
*8.A.21.2.3









Prohibitin, Wph, of 273 aas.

Eukaryota
Viridiplantae
Prohibitn of Triticum aestivum (Wheat)
*8.A.21.2.4









Signal peptide peptidase of 325 aas and 4 or 5 TMSs

Bacteria
Proteobacteria
Peptidase of Bdellovibrio exovorus