TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*8.A.22.1.1









Voltage-dependent Ca2+ channel (VSCC) β1-subunit, CACNB1 of 597 aas.  VSCCs are composed of different subunits, α1, β, α2δ and γ, among which the cytosolic β subunit (Cavβ) controls the trafficking of the channel to the plasma membrane, its regulation and its gating properties. Many proteins interact with Cavβ, suggesting a multifunctional role of these proteins. Some of the newly assigned functions of Cavβ are independent of its role in the regulation of VGCC (Rima et al. 2016).

Eukaryota
Metazoa
CACNB1 of Mus musculus (33146398)
*8.A.22.1.2









Voltage-gated Ca2+ channel β2-subunit, CACNB2

Eukaryota
Metazoa
CACNB2 of Homo sapiens (18481641)
*8.A.22.1.3









Dihydropyridine-sensitive L-type, Ca2+ channel β3-subunit, CACNB3. Oligomerization of Cavβ subunits is required for Ca2+ channel activity (Lao et al., 2010).

Eukaryota
Metazoa
CACNB3 of Homo sapiens (1705683)
*8.A.22.1.4









Ca2+ channel, voltage-dependent, β4-subunit, CACNB4

Eukaryota
Metazoa
CACNB4 of Homo sapiens (4502537)