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8.A.27.1.5
CDC50A or TMEM30A of 361 aas and 2 TMSs.  Required for targetting of the ATP11C ATPase (3.A.3.8.14) and probably several other phospholipid flipping ATPases to the plasma membrane, and possibly also for their activities (Segawa et al. 2014).  Forms a heterodimer with ATP8B1 (van der Mark et al. 2014). Signaling networks are regulated by TMEM30A during cell migration, reflecting the regulatory mechanisms underlying tumor migration (Wang et al. 2017). TMEM30A deficiency leads to intrahepatic cholestasis in mice by impairing the expression and localization of bile salt transporters and the expression of related nuclear receptors (Liu et al. 2017).

Accession Number:Q9NV96
Protein Name:Cell cycle control protein 50A
Length:361
Molecular Weight:40684.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate NONE

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAMNYNAKDE VDGGPPCAPG GTAKTRRPDN TAFKQQRLPA WQPILTAGTV LPIFFIIGLI 
61:	FIPIGIGIFV TSNNIREIEI DYTGTEPSSP CNKCLSPDVT PCFCTINFTL EKSFEGNVFM 
121:	YYGLSNFYQN HRRYVKSRDD SQLNGDSSAL LNPSKECEPY RRNEDKPIAP CGAIANSMFN 
181:	DTLELFLIGN DSYPIPIALK KKGIAWWTDK NVKFRNPPGG DNLEERFKGT TKPVNWLKPV 
241:	YMLDSDPDNN GFINEDFIVW MRTAALPTFR KLYRLIERKS DLHPTLPAGR YSLNVTYNYP 
301:	VHYFDGRKRM ILSTISWMGG KNPFLGIAYI AVGSISFLLG VVLLVINHKY RNSSNTADIT 
361:	I