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8.A.28.1.6
A-kinase anchor protein 5, AKAP5; AKAP79, of 427 aas. Associates with to the beta2-adrenergic receptor (beta2-AR) to regulate the beta2-AR signaling pathway.  Also binds directly to TrpV4 (TC# 1.A.4.2.5) (Mack and Fischer 2017).

Accession Number:P24588
Protein Name:A-kinase anchor protein 5
Length:427
Molecular Weight:47088.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Membrane1 / Lipid-anchor2
Substrate NONE

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	METTISEIHV ENKDEKRSAE GSPGAERQKE KASMLCFKRR KKAAKALKPK AGSEAADVAR 
61:	KCPQEAGASD QPEPTRGAWA SLKRLVTRRK RSESSKQQKP LEGEMQPAIN AEDADLSKKK 
121:	AKSRLKIPCI KFPRGPKRSN HSKIIEDSDC SIKVQEEAEI LDIQTQTPLN DQATKAKSTQ 
181:	DLSEGISRKD GDEVCESNVS NSTTSGEKVI SVELGLDNGH SAIQTGTLIL EEIETIKEKQ 
241:	DVQPQQASPL ETSETDHQQP VLSDVPPLPA IPDQQIVEEA SNSTLESAPN GKDYESTEIV 
301:	AEETKPKDTE LSQESDFKEN GITEEKSKSE ESKRMEPIAI IITDTEISEF DVTKSKNVPK 
361:	QFLISAENEQ VGVFANDNGF EDRTSEQYET LLIETASSLV KNAIQLSIEQ LVNEMASDDN 
421:	KINNLLQ