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8.A.3.2.4
Capsular polysaccharide type 8 biosynthesis protein Cap8A

Accession Number:P72367
Protein Name:Capsular polysaccharide type 8 biosynthesis protein cap8A
Length:222
Molecular Weight:24867.00
Species:Staphylococcus aureus [1280]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

eggNOG: COG3944
Pfam: PF02706   

Gene Ontology

GO:0005576 C:extracellular region
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015542 F:sugar efflux transmembrane transporter activity
GO:0006859 P:extracellular carbohydrate transport
GO:0009103 P:lipopolysaccharide biosynthetic process
GO:0009405 P:pathogenesis

References (3)

[1] “Cloning of type 8 capsule genes and analysis of gene clusters for the production of different capsular polysaccharides in Staphylococcus aureus.”  Sau S.et.al.   8606192
[2] “Molecular characterization and transcriptional analysis of type 8 capsule genes in Staphylococcus aureus.”  Sau S.et.al.   9045821
[3] “The Staphylococcus aureus allelic genetic loci for serotype 5 and 8 capsule expression contain the type-specific genes flanked by common genes.”  Sau S.et.al.   9245821

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MESTLELTKI KEVLQKNLKI LIILPLLFLI ISAIVTFFVL SPKYQANTQI LVNQTKGDNP 
61:	QFMAQEVQSN IQLVNTYKEI VKSPRILDEV SKDLNNKYSP SKLSSMLTIT NQENTQLINI 
121:	QVKSGHKQDS EKIANSFAKV TSKQIPKIMS LDNVSILSKA DGTAVKVAPK TVVNLIGAFF 
181:	LGLVVALIYI FFKVIFDKRI KDEEDVEKEL GLPVLGSIQK FN