TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


8.A.37.1.2
Human hepcidin (84 aas).  Binds to and inhibits ferroportin (TC#2.A.100.1.4) (Le Gac et al. 2013).  Causes ferroportin internalization and degradation (Rice et al. 2009).

Accession Number:P81172
Protein Name:Hepcidin
Length:84
Molecular Weight:9408.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate NONE

Cross database links:

Structure:
1M4E   1M4F   2KEF   3H0T   4QAE     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MALSSQIWAA CLLLLLLLAS LTSGSVFPQQ TGQLAELQPQ DRAGARASWM PMFQRRRRRD 
61:	THFPICIFCC GCCHRSKCGM CCKT