TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


8.A.4.2.1
MPA2 protein component of an ABC-type capsular polysaccharide export system. (functions with 3.A.1.101.3 (ABC) and 1.B.18.2.3 (OMA)) (Larue et al., 2011)

Accession Number:P32014
Protein Name:CtrB aka NMB0072
Length:387
Molecular Weight:43392.00
Species:Neisseria meningitidis (serogroup B) [491]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate NONE

Cross database links:

HEGENOM: HBG655419
RefSeq: NP_273136.1   
Entrez Gene ID: 902178   
BioCyc: NMEN122586:NMB_0072-MONOMER   
KEGG: nme:NMB0072   

Gene Ontology

GO:0009276 C:Gram-negative-bacterium-type cell wall
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015542 F:sugar efflux transmembrane transporter acti...
GO:0006859 P:extracellular carbohydrate transport
GO:0015774 P:polysaccharide transport

References (2)

[1] “Evidence for a common molecular origin of the capsule gene loci in Gram-negative bacteria expressing group II capsular polysaccharides.”  Frosch M.et.al.   1659649
[2] “Complete genome sequence of Neisseria meningitidis serogroup B strain MC58.”  Tettelin H.et.al.   10710307

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSEQLPVAVA TETKAERKKP KKKSWIKKLS PLFWVTVIIP TVISLVYFGF FASDRFTSQS 
61:	SFVVRSPKSQ SSLNGLGAIL QGTGFARAQD DIYTVGEYMR SRSSLDELRK ILPVREFYET 
121:	KGDAFSRFNG FGFRGEEEAF YQYYKNQVMI NFDTVSGIST LNVTSFDALE SKKINEALLK 
181:	QGEALINQLN DRARADTVRY AEEVVKTAAE RVKEASQNLT DYRIANGVFD LKAQSEVQMG 
241:	LVSKLQDELI VIQTQLDQVK AVTPENPQIP GLQAREQSLR KEIDQQLRAI SGGGHSSLSN 
301:	QAAEYQRVYL ENQLAEQQLA AAMTSLESAK VEADRQQLYL EVISQPSLPD LAHEPKRLYN 
361:	IVATLIIGLM VYGILSLLTA SIREHKN